Evidence map›Paper›PMID 31641224›Full record

ArticleLaboratory investigation; a journal of technical methods and pathology2020

Interleukin-33 delays recovery of mucosal inflammation via downregulation of homeostatic ABCG5/8 in the colon.

Yoshiyuki Mishima, Hiroki Sonoyama, Shunji Ishihara, Naoki Oshima, Ichiro Moriyama, Kousaku Kawashima, Yoshikazu Kinoshita

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Laboratory investigation; a journal of technical methods and pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yoshiyuki Mishima *Department of Internal Medicine II, Shimane University Faculty of Medicine, Izumo, Japan.
Hiroki Sonoyama *Department of Internal Medicine II, Shimane University Faculty of Medicine, Izumo, Japan.
Shunji IshiharaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, Izumo, Japan. si360405@med.shimane-u.ac.jp.
Naoki OshimaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, Izumo, Japan.
Ichiro MoriyamaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, Izumo, Japan.
Kousaku KawashimaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, Izumo, Japan.ORCID http://orcid.org/0000-0002-5815-0066
Yoshikazu KinoshitaDepartment of Internal Medicine II, Shimane University Faculty of Medicine, Izumo, Japan.
Shimane University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have suggested that interleukin-33 (IL-33) is involved in the pathogenesis of ulcerative colitis (UC), though the detailed mechanisms are not fully known. We investigated IL-33-mediated colonic homeostasis using a mechanistic method. Il33

Indexed as

AnimalsATP Binding Cassette Transporter, Subfamily G, Member 5ATP Binding Cassette Transporter, Subfamily G, Member 8Caco-2 CellsColonDown-RegulationHumansInflammationInterleukin-33Intestinal MucosaLipoproteinsMiceMice, Inbred BALB CABCG5 protein, mouseABCG8 protein, mouseATP Binding Cassette Transporter, Subfamily G, Member 5ATP Binding Cassette Transporter, Subfamily G, Member 8IL33 protein, humanIl33 protein, mouseInterleukin-33Lipoproteins

Identifiers

PMID31641224
OpenAlexW2981830443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.