Evidence map›Paper›PMID 31641221›Full record

ArticleScientific reports2019

Phenomics reveals a novel putative chloroplast fatty acid transporter in the marine diatom Skeletonema marinoi involved in temperature acclimation.

Oskar N Johansson, Mats Töpel, Jenny Egardt, Matthew I M Pinder, Mats X Andersson, Anna Godhe, Adrian K Clarke

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Oskar N JohanssonDepartment of Biological and Environmental Sciences, University of Gothenburg, Box 461, 40530, Gothenburg, Sweden.
Mats TöpelDepartment of Marine Sciences, University of Gothenburg, Box 462, 40530, Gothenburg, Sweden.ORCID http://orcid.org/0000-0001-7989-696X
Jenny EgardtDepartment of Biological and Environmental Sciences, University of Gothenburg, Box 461, 40530, Gothenburg, Sweden.
Matthew I M PinderDepartment of Marine Sciences, University of Gothenburg, Box 462, 40530, Gothenburg, Sweden.
Mats X AnderssonDepartment of Biological and Environmental Sciences, University of Gothenburg, Box 461, 40530, Gothenburg, Sweden.
Anna GodheDepartment of Marine Sciences, University of Gothenburg, Box 462, 40530, Gothenburg, Sweden.
Adrian K ClarkeDepartment of Biological and Environmental Sciences, University of Gothenburg, Box 461, 40530, Gothenburg, Sweden. adrian.clarke@bioenv.gu.se.
University of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diatoms are the dominant phytoplankton in temperate oceans and coastal regions and yet little is known about the genetic basis underpinning their global success. Here, we address this challenge by developing the first phenomic approach for a diatom, screening a collection of randomly mutagenized but identifiably tagged transformants. Based upon their tolerance to temperature extremes, several compromised mutants were identified revealing genes either stress related or encoding hypothetical proteins of unknown function. We reveal one of these hypothetical proteins is a novel putative chloroplast fatty acid transporter whose loss affects several fatty acids including the two omega-3, long-chain polyunsaturated fatty acids - eicosapentaenoic and docosahexaenoic acid, both of which have medical importance as dietary supplements and industrial significance in aquaculture and biofuels. This mutant phenotype not only provides new insights into the fatty acid biosynthetic pathways in diatoms but also highlights the future value of phenomics for revealing specific gene functions in these ecologically important phytoplankton.

Indexed as

AcclimatizationEcosystemPhenomicsTemperatureChloroplastsDiatomsFatty AcidsGenomeMembrane Transport ProteinsMutagenesis, InsertionalMutationTransformation, GeneticFatty AcidsMembrane Transport Proteins

Identifiers

PMID31641221
PMCPMC6805942
OpenAlexW2981757771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.