Evidence map›Paper›PMID 31641138›Full record

ArticleNature communications2019

A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila.

H Babski, T Jovanic, C Surel, S Yoshikawa, M F Zwart, J Valmier, J B Thomas, J Enriquez, P Carroll, A Garcès

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

H BabskiInserm U1051, Institute for Neurosciences of Montpellier, University of Montpellier, 34295, Montpellier, France. helene.babski@inserm.fr.
T JovanicParis-Saclay Institute of Neuroscience, UMR 9717, 1 avenue de la Terrasse, 91190, Gif-sur-Yvette, France.
C SurelInserm U1051, Institute for Neurosciences of Montpellier, University of Montpellier, 34295, Montpellier, France.
S YoshikawaMolecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.
M F ZwartSchool of Psychology and Neuroscience, University of St Andrews, St Andrews, KY16 9JP, UK.ORCID http://orcid.org/0000-0002-5073-8631
J ValmierInserm U1051, Institute for Neurosciences of Montpellier, University of Montpellier, 34295, Montpellier, France.
J B ThomasMolecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.
J EnriquezInstitut de Génomique Fonctionnelle de Lyon (IGFL), École Normale Supérieure de Lyon and Centre National de la Recherche Scientifique (CNRS), 32 avenue Tony Garnier, 69007, Lyon, France.
P CarrollInserm U1051, Institute for Neurosciences of Montpellier, University of Montpellier, 34295, Montpellier, France.ORCID http://orcid.org/0000-0003-3287-8195
A GarcèsInstitut de Génomique Fonctionnelle de Lyon (IGFL), École Normale Supérieure de Lyon and Centre National de la Recherche Scientifique (CNRS), 32 avenue Tony Garnier, 69007, Lyon, France. alain.garces@inserm.fr.
Inserm · FRCentre National de la Recherche Scientifique · FRSalk Institute for Biological Studies · USÉcole Normale Supérieure de Lyon · FRUniversity of St Andrews · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interneurons (INs) coordinate motoneuron activity to generate appropriate patterns of muscle contractions, providing animals with the ability to adjust their body posture and to move over a range of speeds. In Drosophila larvae several IN subtypes have been morphologically described and their function well documented. However, the general lack of molecular characterization of those INs prevents the identification of evolutionary counterparts in other animals, limiting our understanding of the principles underlying neuronal circuit organization and function. Here we characterize a restricted subset of neurons in the nerve cord expressing the Maf transcription factor Traffic Jam (TJ). We found that TJ

Indexed as

AnimalsAnimals, Genetically ModifiedDrosophilaDrosophila ProteinsEmbryo, Nonmammaliangamma-Aminobutyric AcidGene Expression RegulationGene SilencingInterneuronsLarvaLocomotionMaf Transcription Factors, LargeMotor ActivityProto-Oncogene ProteinsSpinal Nerve RootsDrosophila Proteinsgamma-Aminobutyric AcidMaf Transcription Factors, LargeProto-Oncogene Proteinstj protein, Drosophila

Identifiers

PMID31641138
PMCPMC6805931
OpenAlexW2982253782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.