Evidence map›Paper›PMID 31641132›Full record

ArticleScientific data2019

16S rDNA based skin microbiome data of healthy individuals and leprosy patients from India.

Nitin Bayal, Sunil Nagpal, Mohammed Monzoorul Haque, Milind S Patole, Vijayalakshmi Valluri, Rohini Suryavanshi, Sharmila S Mande, Shekhar C Mande

Open access · goldAbstract read
In one paragraph

Article in Scientific data, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
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  4. Article
  5. Skin microbiome profile in people living with HIV/AIDS in Cameroon.Frontiers in cellular and infection microbiology · 2023
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nitin BayalNational Centre for Cell Science, NCCS Complex, Pune, India.
Sunil NagpalBioSciences R&D, TCS Research, Tata Consultancy Services, Pune, India.ORCID http://orcid.org/0000-0001-9221-1443
Mohammed Monzoorul HaqueBioSciences R&D, TCS Research, Tata Consultancy Services, Pune, India.
Milind S PatoleNational Centre for Cell Science, NCCS Complex, Pune, India.
Vijayalakshmi ValluriImmunology & Molecular Biology Department, Bhagwan Mahavir Medical Research Centre, A. C. Guards, Hyderabad, Telangana State, India.
Rohini SuryavanshiRichardson Leprosy Hospital (The Leprosy Mission Trust), Miraj, Maharashtra, India.
Sharmila S MandeBioSciences R&D, TCS Research, Tata Consultancy Services, Pune, India.
Shekhar C MandeCouncil of Scientific & Industrial Research, Anusandhan Bhawan, 2, Rafi Marg, New Delhi, India. shekhar@csir.res.in.ORCID http://orcid.org/0000-0002-6634-0820
Tata Consultancy Services (India) · INNational Centre for Cell Science · IN

Funding

Department of Biotechnology, Ministry of Science and Technology (DBT) DBT/PR15450/COE/34/46/2016Department of Biotechnology, Ministry of Science and Technology (DBT) DBT/PR3260/BRB/10/967/2011Department of Biotechnology, Ministry of Science and Technology (DBT) JRF/SRF
6 · The paper itself

Abstract

Leprosy is an infectious disease that has predilection in skin and peripheral nerves. Skin has its own microbiome, however it is not extensively studied in Indian leprosy patients. Here, by using next-generation 16S rDNA sequencing, we have attempted to assess the skin associated microbial diversity pertaining to affected and unaffected skin of Indian leprosy patients. A total of 90 skin swab samples were collected from 60 individuals (30 healthy controls, 30 patients) residing in Hyderabad and Miraj, two distinct geographical locations in India to assess the homo/heterogeneity of skin microbial signatures. While a large increase in genus Methylobacterium and Pseudomonas was seen in patients from Miraj and Hyderabad respectively, a considerable decrease in genus Staphylococcus in the leprosy patients (as compared to controls) from both geographical locations was also observed. We expect that, these datasets can not-only provide further interesting insights, but will also help to observe dynamics of microbiome in the diseased state and generate hypotheses to test for skin microbiome transplantation studies in leprosy.

Identifiers

PMID31641132
PMCPMC6805899
OpenAlexW2981950958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.