SynthesisNature communications2019
Hyperdirect insula-basal-ganglia pathway and adult-like maturity of global brain responses predict inhibitory control in children.
Synthesis in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Bayesian dynamical system analysis of the effects of methylphenidate in children with attention-deficit/hyperactivity disorder: a randomized trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Trial
- Methylphenidate Enhances Spontaneous Fluctuations in Reward and Cognitive Control Networks in Children With Attention-Deficit/Hyperactivity Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Trial
- Methylphenidate remediates aberrant brain network dynamics in children with attention-deficit/hyperactivity disorder: A randomized controlled trial.NeuroImage · 2022Trial
- Nonergodicity and Simpson's paradox in neurocognitive dynamics of cognitive control.Nature communications · 2026Article
- Dynamic modeling in neurocognitive frameworks of childhood ADHD: a review of inhibitory control and reward systems.Translational psychiatry · 2026Review
- SHAP-based explainable machine learning analysis of reward-related neural connectivity to predict preadolescent irritability.Neuroimage. Reports · 2026Article
- Inhibition-related connectivity predicts irritability risk and resilience across early adolescence.Social cognitive and affective neuroscience · 2026Article
- Unraveling the mystery of stuttering: clinical and physiological insights into its manifestation.Frontiers in human neuroscience · 2026Article
- Hierarchical Organization of Bilateral Prefrontal-Basal Ganglia Circuits for Response Inhibition Control.Human brain mapping · 2025Article
- Multi-voxel pattern analysis for developmental cognitive neuroscientists.Developmental cognitive neuroscience · 2025Review
- Reduced recruitment of inhibitory control regions in very young children with ADHD during a modified Kiddie Continuous Performance Task: A fMRI study.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Reduced temporal and spatial stability of neural activity patterns predict cognitive control deficits in children with ADHD.Nature communications · 2025Article
- Neural mechanisms of reward processing in preadolescent irritability: Insights from the ABCD study.Journal of affective disorders · 2025Article
- Neural mechanisms of inhibitory control in preadolescent irritability: Insights from the ABCD study.Biological psychology · 2024Article
- Article
- Reduced temporal and spatial stability of neural activity patterns predict cognitive control deficits in children with ADHD.bioRxiv : the preprint server for biology · 2024Article
- Subthalamic nucleus-language network connectivity predicts dopaminergic modulation of speech function in Parkinson's disease.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- A multi-demand operating system underlying diverse cognitive tasks.Nature communications · 2024Article
- Both reactive and proactive control are deficient in children with ADHD and predictive of clinical symptoms.Translational psychiatry · 2023Article
- Dopaminergic medication normalizes aberrant cognitive control circuit signalling in Parkinson's disease.Brain : a journal of neurology · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Inhibitory control is fundamental to children's self-regulation and cognitive development. Here we investigate cortical-basal ganglia pathways underlying inhibitory control in children and their adult-like maturity. We first conduct a comprehensive meta-analysis of extant neurodevelopmental studies of inhibitory control and highlight important gaps in the literature. Second, we examine cortical-basal ganglia activation during inhibitory control in children ages 9-12 and demonstrate the formation of an adult-like inhibitory control network by late childhood. Third, we develop a neural maturation index (NMI), which assesses the similarity of brain activation patterns between children and adults, and demonstrate that higher NMI in children predicts better inhibitory control. Fourth, we show that activity in the subthalamic nucleus and its effective connectivity with the right anterior insula predicts children's inhibitory control. Fifth, we replicate our findings across multiple cohorts. Our findings provide insights into cortical-basal ganglia circuits and global brain organization underlying the development of inhibitory control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.