Evidence map›Paper›PMID 31641054›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease.

Isabelle R de Luzy, Jonathan C Niclis, Carlos W Gantner, Jessica A Kauhausen, Cameron P J Hunt, Charlotte Ermine, Colin W Pouton, Lachlan H Thompson, Clare L Parish

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Properties and Application of Pseudotyped Lentiviral Vectors.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Article
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  6. Wrap it up: myelination of transplanted neurons for repair.Frontiers in cellular neuroscience · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Isabelle R de LuzyFlorey Institute of Neuroscience and Mental Health, Parkville, 3052 Victoria, Australia, and.
Jonathan C NiclisFlorey Institute of Neuroscience and Mental Health, Parkville, 3052 Victoria, Australia, and.
Carlos W GantnerFlorey Institute of Neuroscience and Mental Health, Parkville, 3052 Victoria, Australia, and.ORCID 0000-0003-0825-7786
Jessica A KauhausenFlorey Institute of Neuroscience and Mental Health, Parkville, 3052 Victoria, Australia, and.
Cameron P J HuntFlorey Institute of Neuroscience and Mental Health, Parkville, 3052 Victoria, Australia, and.
Charlotte ErmineFlorey Institute of Neuroscience and Mental Health, Parkville, 3052 Victoria, Australia, and.
Colin W PoutonMonash Institute of Pharmaceutical Sciences, Monash University, Parkville, 3052 Victoria, Australia.
Lachlan H ThompsonFlorey Institute of Neuroscience and Mental Health, Parkville, 3052 Victoria, Australia, and.ORCID 0000-0003-2632-0304
Clare L ParishFlorey Institute of Neuroscience and Mental Health, Parkville, 3052 Victoria, Australia, and clare.parish@florey.edu.au.ORCID 0000-0001-8212-9884
Florey Institute of Neuroscience and Mental Health · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human pluripotent stem cells (hPSCs) are a promising resource for the replacement of degenerated ventral midbrain dopaminergic (vmDA) neurons in Parkinson's disease. Despite recent advances in protocols for the

Indexed as

AnimalsCell LineFemaleForecastingHumansLIM-Homeodomain ProteinsMaleMesencephalonMiceMice, Inbred BALB CMice, NudeParkinsonian DisordersPluripotent Stem CellsRatsRats, NudeStem Cell TransplantationLIM-Homeodomain ProteinsLMX1A protein, humanTranscription Factorscell sortingdopamineLMX1AParkinson's diseasePITX3transplantion

Identifiers

PMID31641054
PMCPMC6880462
OpenAlexW2981484918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.