ArticleBMJ open2019
Cohort profile: the Biology, Affect, Stress, Imaging and Cognition (BASIC) study on perinatal depression in a population-based Swedish cohort.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Labour epidural analgesia and early childhood behavioural outcomes: the moderating role of maternal mental health and pro-inflammatory cytokines.Anaesthesia · 2026Article
- The role of gene-environment interactions in endocrine-sensitive life stages for shaping mental health: focus on the RE-MEND project.Frontiers in psychiatry · 2026Review
- Association between perinatal depressive symptoms and parental cohabitation status in a Nordic high-income country.PloS one · 2026Article
- Psychosocial risk factors for depression and anxiety in European postpartum women: A scoping review.European journal of midwifery · 2026Review
- Predicting allergy and postpartum depression from an incomplete compositional microbiome.BMC genomics · 2025Article
- Differentially expressed transcripts associated with depressive symptoms during pregnancy and postpartum.Molecular psychiatry · 2025Article
- Do the early social environment and persistent peripartum depressive symptoms shape toddlers' expressive language?JCPP advances · 2025Article
- Psychometric Evaluation of the Swedish Version of the Child Behaviour Check List (CBCL) 1.5-5.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Trajectories and dimensional phenotypes of depressive symptoms throughout pregnancy and postpartum in relation to prior premenstrual symptoms.The British journal of psychiatry : the journal of mental science · 2025Article
- Investigating the Microbiome in Relation to Mental Distress Across Two Points During Pregnancy: Data From U.S. and Swedish Cohorts.Biological psychiatry global open science · 2025Article
- Elevated Plasma Level of Arginine and Its Metabolites at Labor Among Women With Preeclampsia: A Prospective Cohort Study.American journal of hypertension · 2025Article
- Association of estrogen receptor single nucleotide polymorphisms and perinatal depression.PloS one · 2025Article
- Peripartum depression symptom trajectories, telomere length and genotype, and adverse childhood experiences.BMC psychiatry · 2024Article
- Investigating heart rate variability measures during pregnancy as predictors of postpartum depression and anxiety: an exploratory study.Translational psychiatry · 2024Article
- Sex-Specific Transcriptomic Changes in the Villous Tissue of Placentas of Pregnant Women Using a Selective Serotonin Reuptake Inhibitor.ACS chemical neuroscience · 2024Article
- Differential gene expression in two consecutive pregnancies between same sex siblings and implications on maternal constraint.Scientific reports · 2024Article
- Feeling better? - Identification, interventions, and remission among women with early postpartum depressive symptoms in Sweden: a nested cohort study.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- Remission or Persistence? A Prediction Tool to Identify Women at Risk for Long-Term Depressive Symptoms Postpartum.Depression and anxiety · 2024Article
- Personality vulnerability to depression, resilience, and depressive symptoms: epigenetic markers among perinatal women.Upsala journal of medical sciences · 2024Article
- Cohort profile: the U-BIRTH study on peripartum depression and child development in Sweden.BMJ open · 2023Article
Corrections and comments
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Authors and funding
13 authors.
Funding
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Abstract
purposeWith the population-based, prospective Biology, Affect, Stress, Imaging and Cognition (BASIC) cohort, we aim to investigate the biopsychosocial aetiological processes involved in perinatal depression (PND) and to pinpoint its predictors in order to improve early detection.
participantsFrom September 2009 to November 2018, the BASIC study at Uppsala University Hospital, Sweden, has enrolled 5492 women, in 6478 pregnancies, of which 46.3% first-time pregnancies and with an average age of 31.5 years. After inclusion around gestational week 16-18, participants are followed-up with data collection points around gestational week 32, at childbirth, as well as three times postpartum: after 6 weeks, 6 months and 1 year. At the last follow-up, 70.8% still remain in the cohort. FINDINGS TO DATE: In addition to internet-based surveys with self-report instruments, participants contribute with biological samples, for example, blood samples (maternal and from umbilical cord), biopsies (umbilical cord and placenta) and microbiota samples. A nested case-control subsample also takes part in cognitive and emotional tests, heart rate variability tests and bioimpedance tests. Subprojects have identified various correlates of PND of psychological and obstetric origin in addition to factors of the hypothalamic-pituitary-adrenal axis and immune system. FUTURE PLANS: In parallel with the completion of data collection (final follow-up November 2019), BASIC study data are currently analysed in multiple subprojects. Since 2012, we are conducting an ongoing follow-up study on the participants and their children up to 6 years of age (U-BIRTH). Researchers interested in collaboration may contact Professor Alkistis Skalkidou (corresponding author) with their request to be considered by the BASIC study steering committee.
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