ArticleBMJ open2019
Knowledge of and attitudes toward clinical trials in Saudi Arabia: a cross-sectional study.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Factors Affecting Acceptance of Participating in Clinical Trials of New Drugs: A National Cross-Sectional Study.Journal of evidence-based medicine · 2026Article
- Bridging the clinical trial gap in Saudi Arabia: a multi-stakeholder conference-based consensus on strategic initiatives for global competitiveness and patient inclusion.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026Article
- Ethical and Regulatory Awareness of Clinical Trials: A Nationwide Cross-Sectional Study from Poland.Therapeutic innovation & regulatory science · 2026Article
- Knowledge and attitudes toward cancer clinical trials: a multi-national cross-sectional study in the Middle East and North Africa.BMC cancer · 2026Article
- Public Knowledge and Attitudes Towards Clinical Trial Participation: A Mixed-Method Study in Bagamoyo District, Tanzania.International journal of environmental research and public health · 2026Article
- Mapping Health Research Involving Human Subjects in Saudi Arabia:Saudi medical journal · 2026Article
- Assessment of Participant Satisfaction and Overall Experience: A Cross-Sectional Survey to Inform Trial Conduct.Patient preference and adherence · 2026Article
- Attitudes Toward COVID-19 Vaccination and Clinical Trials Among Saudi University Students.Journal of epidemiology and global health · 2025Article
- Article
- Knowledge and perception of a clinical trial among the participants: An experience from oral cholera vaccine study in Koshi Province, Nepal.Human vaccines & immunotherapeutics · 2024Article
- Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourth-Year PharmD Undergraduates from Riyadh, Saudi Arabia.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Factors influencing willingness to participate in ophthalmic clinical trials and strategies for effective recruitment.International journal of ophthalmology · 2024Article
- Article
- Knowledge and Attitude towards Clinical Trials among General Population of Northern Saudi Arabia during COVID-19 Era: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2023Article
- Factors that influence a patient's decision to engage in genetic research.Frontiers in public health · 2023Article
- Considering intermittent fasting among Saudis: insights into practices.BMC public health · 2022Article
- Knowledge, attitude, and perception of public about participation in COVID-19 clinical trials: a study from Egypt and Saudi Arabia.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022Article
- The Characteristics of Clinical Studies Submitted to the Saudi Food and Drug Authority from 2009 until 2020.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021Article
- Clinical trials: Predictors of knowledge and attitudes towards participation.International journal of clinical practice · 2021Article
- Impact of COVID-19 on Public Knowledge and Attitudes Toward Participating in Clinical Trials in Saudi Arabia: A Cross-Sectional Study.International journal of general medicine · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesClinical trials (CTs) are considered an important method for developing new treatments and providing access to potentially effective drugs that are still under investigation. Measuring the public's knowledge of and attitudes toward CTs is important for assessing their readiness for and acceptance of human drug testing, which has previously not been assessed in the Kingdom of Saudi Arabia (KSA). The objective of this study is to explore the Saudi public's knowledge of and attitudes toward CTs as well as participation in trials to test new or approved drugs.
designCross-sectional.
settingThe 2016 Al Jenadriyah cultural/heritage festival in Riyadh, KSA.
participantsParticipating booths and exhibition halls, as well as festival visitors, were approached to participate in the study. PRIMARY AND SECONDARY OUTCOME MEASURES: Knowledge of and attitudes toward CTs.
resultsThe final number of participants was 938. The responses were converted to a percentage mean score (out of 100) for each knowledge-related response and attitude. The total mean knowledge score was 56.8±24.8 and the attitude-related score was 61.5±28.0. Although most of the participants supported testing approved or off-label and new drugs on adult and paediatric patients, only a third (30.5%) agreed that new drugs could be tested on healthy volunteers. The results indicated that gender, educational level, income, medical background, age and health insurance were independently associated with the level of knowledge of CTs. In terms of attitudes toward CTs, the factors that were independently associated were gender, educational level and medical background.
conclusionsThe Saudi public has a low level of knowledge and a moderately positive attitude toward CTs. There is a moderate positive correlation between the two factors such that as knowledge of CTs increases, the Saudi public will hold more positive attitudes toward CTs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.