Evidence map›Paper›PMID 31640995›Full record

ArticleBMJ open2019

Prevalence and characteristics of polycystic ovary syndrome in Brazilian women: protocol for a nation-wide case-control study.

Poli Mara Spritzer, Lucas B Marchesan, Betânia R Santos, Felipe V Cureau, Karen Oppermann, Rosana Maria Dos Reis, Rui A Ferriani, Rita Weiss, Ricardo Meirelles, Ana Lucia Candido and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Poli Mara SpritzerDepartment of Physiology and Postgraduate Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil spritzer@ufrgs.br.ORCID 0000-0002-6734-7688
Lucas B MarchesanDepartment of Physiology and Postgraduate Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Betânia R SantosPostgraduate Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Felipe V CureauPostgraduate Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Karen OppermannDepartment of Gynecology and Obstetrics, Universidade de Passo Fundo, Passo Fundo, Brazil.
Rosana Maria Dos ReisDepartment of Gynecology and Obstetrics Ribeirao Preto, Universidade de Sao Paulo Campus de Ribeirao Preto, Ribeirao Preto, Brazil.
Rui A FerrianiDepartment of Gynecology and Obstetrics Ribeirao Preto, Universidade de Sao Paulo Campus de Ribeirao Preto, Ribeirao Preto, Brazil.
Rita WeissInstituto Estadual de Diabetes e Endocrinologia Luiz Capriglione, Rio de Janeiro, Brazil.
Ricardo MeirellesInstituto Estadual de Diabetes e Endocrinologia Luiz Capriglione, Rio de Janeiro, Brazil.
Ana Lucia CandidoDepartment of Gynecology and Obstetrics, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Fernando M ReisDepartment of Gynecology and Obstetrics, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Brazilian PCOS Network
Universidade Federal do Rio Grande do Sul · BRInstituto Estadual de Diabetes e Endocrinologia Luiz Capriglione · BRUniversidade de Ribeirão Preto · BRUniversidade Federal de Minas Gerais · BRUniversidade de Passo Fundo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBrazil is a large country, with a population of mixed ethnic background and broad variation in dietary and physical activity traits across its five main regions. Because data on Brazilian women with polycystic ovary syndrome (PCOS) are still scarce, a nation-wide collaborative study was designed to determine the prevalence of metabolic and reproductive abnormalities and the presence of anxiety and depression in Brazilian women with PCOS. In addition, the study aims at describing how these characteristics are distributed across PCOS phenotypes and at detecting associations with regional demographic and lifestyle aspects, genetic variants, and epigenetic markers. METHODS AND ANALYSIS: The Brazilian PCOS study is being conducted in the outpatient clinics of eight university hospitals within the public healthcare network (Unified Health System) across the country. Additional centres will be included following completion of the research ethics approval process. The sample includes women with PCOS according to Rotterdam criteria at inclusion in the study and a control group of healthy women matched by age, socioeconomic status and geographical region. Data will be collected in each centre and incorporated into a unified cloud database. Clinical, demographic, socioeconomic, psychological, metabolic, epigenetic and genotypic variables will be evaluated. The data resulting from this study will be useful to guide specific public strategies for primary and secondary prevention of metabolic and reproductive comorbidities in the PCOS population of Brazil. ETHICS AND DISSEMINATION: The study protocol was approved by each local Research Ethics Committee. Written informed consent will be obtained from each participant. During data collection, analysis and publication, care will be taken to ensure confidentiality of participant information. Study results will be published in peer-reviewed journals and disseminated at international conferences. This research protocol was registered with the Research Ethics Committee of HCPA, through Plataforma Brasil. TRIAL REGISTRATION NUMBER: CAAE 18082413.9.1001.5327.

Indexed as

BrazilCase-Control StudiesFemaleHumansMedical History TakingOutpatient Clinics, HospitalPhysical ExaminationPolycystic Ovary SyndromePrevalenceProspective StudiesResearch DesignSurveys and QuestionnairesBrazilepigeneticslifestylePCOSphenotypespolycystic ovary syndrome

Identifiers

PMID31640995
PMCPMC6830701
OpenAlexW2981718124

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.