Evidence map›Paper›PMID 31640960›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2019

[Inhibitory effect of connexin43 protein on autophagy in cisplatin-resistant testicular cancer I-10 cells].

Min Yuan, Shuying Dong, Yanxue Yao, Yunzheng Men, Kaijin Mao, Xuhui Tong

Abstract read
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Min YuanSchool of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Shuying DongSchool of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Yanxue YaoSchool of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Yunzheng MenSchool of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Kaijin MaoSchool of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Xuhui TongSchool of Pharmacy, Bengbu Medical College, Bengbu 233030, China.
Bengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of connexin43 (Cx43) protein on autophagy in cisplatin (DDP)-resistant testicular cancer I-10 cells.

methodsThe expression of Cx43 proteins in testicular cancer I-10 cells and I-10/DDP cells were detected with Western blotting. I-10/DDP cells were transfected with a full- length mouse Cx43 vector (mCx43)

resultsCx43 was significantly decreased in I-10/DDP cells compared with I-10 cells (

conclusionsCx43 inhibits autophagy in cisplatin-resistant testicular cancer I-10 /DDP cells.

Indexed as

AutophagyDrug Resistance, NeoplasmAnimalsCell Line, TumorCisplatinConnexin 43MaleMiceTesticular NeoplasmsCisplatinConnexin 43autophagycisplatinumconnexin43gap junctiontestis

Identifiers

PMID31640960
PMCPMC6881733
OpenAlexW2984659904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.