ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2019
[Effects of glycosylated hemoglobin and disease course on islet β-cell function in patients with type 2 diabetes].
Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Sex differences in islet stress responses support female β cell resilience.Molecular metabolism · 2023Article
- Association Between Hemoglobin Glycation Index and Metabolic Syndrome in Middle-Aged and Older People.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
objectiveTo compare islet β-cell function in type 2 diabetic (T2DM) patients with different glycosylated hemoglobin (HbA1c) levels and diabetes durations.
methodsWe examined body parameters, biochemical profiles and islet autoantibodies in a total of 803 T2DM patients admitted in the Department of Endocrinology of the First Affiliated Hospital of Nanjing Medical University between December, 2014 and April, 2016. The patients were stratified by HbA1c level and disease course and underwent steamed bun test to evaluate islet β-cell function and insulin resistance.
resultsLinear correlation analysis showed that in T2DM patients, HbA1c level was negatively correlated with HOMA2-IR, HOMA2-%β, DI30 and DI180 (
conclusionsThe secretion function of islet β cells decreases progressively with the increase of HbA1c level or disease course in T2DM patients, but the disease course does not appear to have an effect as strong as that of HbA1c level on islet β cell function.
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