Evidence map›Paper›PMID 31640775›Full record

ArticleBMC research notes2019

Chromogenic medium versus PCR-RFLP in the speciation of Candida: a comparative study.

Sankar Leena Sankari, Krishnan Mahalakshmi, Venkatesan Naveen Kumar

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Detection of Fluconazole Resistance inJournal of fungi (Basel, Switzerland) · 2025
    Article
  2. Rapid Identification of Clinically RelevantJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. The impact of increasing non-albicans Candida trends on diagnostics in immunocompromised patients.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  4. Article
  5. The burden of serious fungal infections in Azerbaijan.Therapeutic advances in infectious disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sankar Leena SankariDepartment of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Velachery-Tambaram Road, Chennai, 600100, India.
Krishnan MahalakshmiDepartment of Microbiology/Research Lab for Oral‑Systemic Health, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Velachery-Tambaram Road, Chennai, Tamilnadu, 600100, India. kmagvenkat@gmail.com.ORCID http://orcid.org/0000-0003-2753-9092
Venkatesan Naveen KumarImmuGenix Biosciences Pvt Ltd, No 16/2 Nattal Garden 1st Street, Perambur, Chennai, 600011, Tamil Nadu, India.
Sree Balaji Dental College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCandida species is implicated in a wide array of clinical infections. Speciation of Candida strains is of prime importance in the epidemiological survey and laboratory diagnosis as there is an upswing of antifungal resistance and changing trends in the antifungal resistance pattern among C. albicans and non albicans Candida. Varied phenotypic methods are available for the identification of Candida species which vary in principles and cost factors. Chromogenic agar medium (HiCrome Candida differential agar) is one of the preferred phenotypic methods in limited resource laboratories. Hence, this study was aimed to assess the reliability of HiCrome Candida differential agar, M1297A (HiMedia) in the identification of Candida species compared polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Oral Candida isolates (n = 194) were inoculated onto HiCrome Candida differential agar and the potential of Candida differential Agar was compared with PCR-RFLP.

resultsThe results were not in agreement with PCR-RFLP. Percentage of disagreement was 40.2, 50.0, 100.0 and 25.0 for Candida albicans, Candida krusei, Candida glabrata and Candida tropicalis respectively. PCR-RFLP demonstrated a very high discriminatory power in the identification of Candida species compared to agar.

Indexed as

Polymorphism, Restriction Fragment LengthAgarCandidaCandida albicansCandida glabrataCandida tropicalisCandidiasisChromogenic CompoundsCulture MediaHumansPolymerase Chain ReactionReproducibility of ResultsSensitivity and SpecificitySpecies SpecificityAgarChromogenic CompoundsCulture MediaCandidaHiCrome Candida differential agarPCR–RFLP

Identifiers

PMID31640775
PMCPMC6805376
OpenAlexW2981736330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.