Evidence map›Paper›PMID 31640663›Full record

ArticleBMC urology2019

Safety and efficacy of Holmium laser enucleation of the prostate (HoLEP) in patients with previous transperineal biopsy (TPB): outcomes from a dual-centre case-control study.

Chris Bell, Sacha L Moore, Amarit Gill, Obinna Obi-Njoku, Stephen F Hughes, Asad Saleemi, Gidon Ellis, Farooq Khan, Iqbal S Shergill

Abstract readMulticenter Study
In one paragraph

Article in BMC urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chris BellDepartment of Urology, Wrexham Maelor Hospital, Wrexham, Wales, UK. christopher.bell@wales.nhs.uk.ORCID http://orcid.org/0000-0002-3587-5339
Sacha L MooreDepartment of Urology, Wrexham Maelor Hospital, Wrexham, Wales, UK.
Amarit GillDepartment of Urology, Wrexham Maelor Hospital, Wrexham, Wales, UK.
Obinna Obi-NjokuNorth Wales Clinical Research Centre, Gwenfro, Wrexham Technology Park, Wrexham, LL13 7YP, UK.
Stephen F HughesNorth Wales Clinical Research Centre, Gwenfro, Wrexham Technology Park, Wrexham, LL13 7YP, UK.
Asad SaleemiDepartment of Urology, Luton and Dunstable University Hospital, Lewsey Road, Luton, LU4 0DZ, UK.
Gidon EllisDepartment of Urology, Luton and Dunstable University Hospital, Lewsey Road, Luton, LU4 0DZ, UK.
Farooq KhanDepartment of Urology, Luton and Dunstable University Hospital, Lewsey Road, Luton, LU4 0DZ, UK.
Iqbal S ShergillDepartment of Urology, Wrexham Maelor Hospital, Wrexham, Wales, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated the surgical feasibility, safety and effectiveness of 50 W (low power) Holmium Laser enucleation of the prostate (HoLEP) in patients who have undergone previous template biopsy of the prostate (TPB).

methodsData encompassing pre-operative baseline characteristics, intra-operative measures and post-operative outcomes was collected for 109 patients undergoing HoLEP across two UK centres. Patients were stratified into two groups; group 1 (n = 24) had undergone previous TPB were compared with 'controls' (no previous TPB) in group 2 (n = 85). The primary outcome was successful HoLEP.

resultsThere were no statistically significant differences in either key baseline characteristics or mass of prostate enucleated between groups 1 and 2. There was no statistically significant difference in enucleation or morcellation times parameters between the two groups other than enucleation efficiency in favour of group 1 (p = 0.024). Functional outcomes improved, without any statistically significant difference, in both groups.

conclusionsIn patients with a previous TPB, HoLEP is surgically feasible, safe and effective. TPB should not be considered a contraindication to HoLEP. Our work provides a strong foundation for further research in this area.

Indexed as

AgedBiopsyCase-Control StudiesFeasibility StudiesHumansLasers, Solid-StateMaleMiddle AgedPerineumProstateProstatectomyProstatic NeoplasmsTreatment OutcomeBenign prostatic enlargement (BPE)Holmium laser Enucleation of the prostate (HoLEP)Lower urinary tract symptoms (LUTS)ProstateTransperineal template biopsyUrinary retention

Identifiers

PMID31640663
PMCPMC6805368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.