Evidence map›Paper›PMID 31640610›Full record

ArticleBMC public health2019

Investigating the association between occupational exposure to asbestos and ovarian carcinoma: results from a pilot study in Germany.

Zara Rajput, Kurt Georg Hering, Thomas Kraus, Andrea Tannapfel, Günter Sonnenschein, Alexandra Centmayer, Katja Radon, Dennis Nowak, Tobias Weinmann

Abstract read
In one paragraph

Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Occupational characterization of workers exposed to asbestos: an integrative review.Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMT
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zara RajputInstitute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Ziemssenstr. 1, 80336, München, Germany.
Kurt Georg HeringDepartment of Diagnostic Radiology, Radiooncology and Nuclear Medicine, Radiological Clinic, Miner's Hospital, Dortmund, Germany.
Thomas KrausInstitute for Occupational, Social and Environmental Medicine, RWTH Aachen University, Aachen, Germany.
Andrea TannapfelInstitute for Pathology, Ruhr University Bochum, Bochum, Germany.
Günter SonnenscheinSachverständiger Asbest, Düsseldorf, Germany.
Alexandra CentmayerGesundheitsvorsorge (GVS), Berufsgenossenschaft Energie Textil Elektro Medienerzeugnisse (BG ETEM), Augsburg, Germany.
Katja RadonInstitute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Ziemssenstr. 1, 80336, München, Germany.
Dennis NowakInstitute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Ziemssenstr. 1, 80336, München, Germany.
Tobias WeinmannInstitute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Ziemssenstr. 1, 80336, München, Germany. tobias.weinmann@med.lmu.de.ORCID http://orcid.org/0000-0002-4582-5191

Funding

Deutsche Gesetzliche Unfallversicherung FB-0257
6 · The paper itself

Abstract

backgroundThe aim of this pilot study was to assess the feasibility of a large-scale epidemiologic investigation elucidating the quantitative association between occupational exposure to asbestos and ovarian cancer in former German asbestos workers.

methodsBetween December 2017 and May 2018, a random sample of one thousand insured woman registered at the health service of a German trade association as formerly occupationally exposed to asbestos were invited to participate in a pilot study. Participation included a phone interview using a standardised questionnaire. The feasibility of the project was evaluated using a priori defined criteria. They included response, number of cases, eligibility of the questionnaire data for exact estimation of asbestos fibre-years, and availability of relevant medical documentation (imaging procedures, medical reports, and histologic materials).

resultsThe response (17%) was clearly below the intended number of 60%. With six tumour suspects, of which two could be confirmed by medical documents, the number of cases was within the expected range of two to eleven cases. Exact asbestos fibre-year estimations could be performed for 29% of all interviewees, but only for one suspected case. Medical documentation could be collected for only few participants, while no histology reports could be obtained for all cases. Thus, only the feasibility criterion of the expected number of cases was fulfilled.

conclusionThe results of the pilot study indicate that the planned project is feasible only to a very limited extent. For further planning of the study, measures to improve recruitment of participants are necessary.

Indexed as

AdultAgedAged, 80 and overAsbestosCarcinomaFeasibility StudiesFemaleGermanyHumansMiddle AgedOccupational DiseasesOccupational ExposureOvarian NeoplasmsPilot ProjectsRisk FactorsAsbestosAsbestosCancer epidemiologyEpidemiological methodsOccupational diseasesOvarian neoplasms

Identifiers

PMID31640610
PMCPMC6805637

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.