Evidence map›Paper›PMID 31640566›Full record

ArticleBMC microbiology2019

Cohabitation is associated with a greater resemblance in gut microbiota which can impact cardiometabolic and inflammatory risk.

Casey T Finnicum, Jeffrey J Beck, Conor V Dolan, Christel Davis, Gonneke Willemsen, Erik A Ehli, Dorret I Boomsma, Gareth E Davies, Eco J C de Geus

Abstract readComparative Study
In one paragraph

Article in BMC microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  4. mSystems · 2024
    Article
  5. Relationship Functioning and Gut Microbiota Composition among Older Adult Couples.International journal of environmental research and public health · 2023
    Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Casey T FinnicumAvera Institute for Human Genetics, Avera McKennan Hospital & University Health Center, Sioux Falls, SD, USA. casey.finnicum@avera.org.ORCID 0000-0001-5959-3961
Jeffrey J BeckAvera Institute for Human Genetics, Avera McKennan Hospital & University Health Center, Sioux Falls, SD, USA.
Conor V DolanAmsterdam Public Health Research Institute, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.
Christel DavisAvera Institute for Human Genetics, Avera McKennan Hospital & University Health Center, Sioux Falls, SD, USA.
Gonneke WillemsenAmsterdam Public Health Research Institute, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.
Erik A EhliAvera Institute for Human Genetics, Avera McKennan Hospital & University Health Center, Sioux Falls, SD, USA.
Dorret I BoomsmaAvera Institute for Human Genetics, Avera McKennan Hospital & University Health Center, Sioux Falls, SD, USA.
Gareth E DaviesAvera Institute for Human Genetics, Avera McKennan Hospital & University Health Center, Sioux Falls, SD, USA.
Eco J C de GeusAmsterdam Public Health Research Institute, Vrije Universiteit Medical Center, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe gut microbiota composition is known to be influenced by a myriad of factors including the host genetic profile and a number of environmental influences. Here, we focus on the environmental influence of cohabitation on the gut microbiota as well as whether these environmentally influenced microorganisms are associated with cardiometabolic and inflammatory burden. We perform this by investigating the gut microbiota composition of various groups of related individuals including cohabitating monozygotic (MZ) twin pairs, non-cohabitating MZ twin pairs and spouse pairs.

resultsA stronger correlation between alpha diversity was found in cohabitating MZ twins (45 pairs, r = 0.64, p = 2.21 × 10

conclusionsThrough the comparison of the microbiota contents of MZ twins with varying cohabitation status and spousal pairs, we showed evidence of environmentally influenced OTUs, one of which had a significant association with cardiometabolic and inflammatory burden scores.

Indexed as

SpousesTwins, MonozygoticAdultAgedBacteriaBiomarkersCardiovascular DiseasesFemaleGastrointestinal MicrobiomeHumansInflammationMaleMiddle AgedNetherlandsPhylogenySequence Analysis, DNABiomarkersCohabitationGut microbiotaTwin genetics

Identifiers

PMID31640566
PMCPMC6805388

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.