Evidence map›Paper›PMID 31640396›Full record

ArticleAIDS care2020

Maternal and child health outcomes in rural South African mothers living with and without HIV.

Karl W le Roux, Joan Christodoulou, Emily C Davis, Linnea Stansert Katzen, Elaine Dippenaar, Mark Tomlinson, Mary Jane Rotheram-Borus

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Karl W le RouxZithulele Training and Reseach Centre, Zithulele Hospital, Eastern Cape, South Africa.ORCID 0000-0002-0554-2111
Joan ChristodoulouDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute, University of California at Los Angeles, Los Angeles, CA, USA.ORCID 0000-0001-6997-1567
Emily C DavisDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute, University of California at Los Angeles, Los Angeles, CA, USA.
Linnea Stansert KatzenZithulele Training and Reseach Centre, Zithulele Hospital, Eastern Cape, South Africa.
Elaine DippenaarZithulele Training and Reseach Centre, Zithulele Hospital, Eastern Cape, South Africa.
Mark TomlinsonDepartment of Psychology, Stellenbosch University, Matieland, South Africa.ORCID 0000-0001-5846-3444
Mary Jane Rotheram-BorusDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute, University of California at Los Angeles, Los Angeles, CA, USA.ORCID 0000-0001-6395-5187
University of California, Los Angeles · USZithulele Hospital · ZAStellenbosch University · ZA

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
Neighborhood Alcohol & HIV Prevention in South African TownshipsR01AA017104 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2007 to 2011
$3.8M
An RCT to Improve the South African Government's Community Health Workers' Capacities to Deliver Evidence-based Interventions for Optimizing HIV Outcomes and Reducing its ComorbiditiesR01MH111391 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2016 to 2020
$2.8M
The Global Partnership for AIDS Behavioral Research: South Africa and U.S.R24AA022919 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2013 to 2017
$2.4M
Post-doctoral HIV Research Training Program for HIV Combination PreventionT32MH109205 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2016 to 2020
$2.3M
NIAAA NIH HHS R01 AA017104NIAAA NIH HHS R24 AA022919NIMH NIH HHS P30 MH058107NIMH NIH HHS R01 MH111391NIMH NIH HHS T32 MH109205
6 · The paper itself

Abstract

In the era of widespread antiretroviral therapy (ART), consequences of being HIV-exposed is unclear for children, especially in rural communities. A population sample of consecutive births (470/493) in the Eastern Cape of South Africa (SA) were recruited and reassessed at five points over the first 24 months. Maternal and child outcomes between mothers living with and without HIV were assessed using multiple linear and logistic regressions. At birth, 28% of the sample was mothers living with HIV and five additional mothers seroconverted. All mothers living with HIV reported taking ART. The rate of depressed mood and IPV was similar across serostatus. However, mothers living with HIV significantly decreased their alcohol use after learning about their pregnancy and were more likely to exclusively breastfeed when compared to mothers without HIV. Despite maternal HIV status, children had similar growth across the first 24 months of life. Future work is needed to assess if these developmental trajectories will persist.

Indexed as

Child HealthMaternal HealthAnti-HIV AgentsBreast FeedingChildFemaleHIV InfectionsHumansMental HealthMothersOutcome Assessment, Health CarePregnancyRural PopulationSouth AfricaYoung AdultAnti-HIV Agentsexclusive breastfeedingHIVHIV exposed childrenruralSouth Africa

Identifiers

PMID31640396
PMCPMC7047533
OpenAlexW2981648440

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.