ArticleNutrients2019
Increasing Energy Flux to Maintain Diet-Induced Weight Loss.
Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Diet-induced thermogenesis does not differ after ingestion of an isoenergetic meal, whereas early-phase thermogenesis differed between athletes and non-athletes.European journal of applied physiology · 2026Article
- Weight Loss Plateau: Reasons, Challenges, and Solutions: A Narrative Review.Health science reports · 2026Article
- An Evaluation of the Effects of the Ruthenium (II)-Uracil Schiff Base Complex on Selected Markers of Glucose Homeostasis in Diet-Induced Prediabetic Male Rats.Pharmaceutics · 2026Article
- Mechanisms of weight recurrence after bariatric surgery.Nutrition & metabolism · 2026Review
- Associations between preoperative resting energy expenditure and postoperative weight loss after metabolic bariatric surgery - a mid-term observational study.BMC surgery · 2026Observational
- Motivating increases in physical activity to prevent recurrence of weight gain after metabolic bariatric surgery: The Exercise Values of Life and Vitality Everyday (EVOLVE) trial.Contemporary clinical trials · 2025Article
- The Role of Physical Activity in Minimizing Recurrence of Weight Gain Following Metabolic and Bariatric Surgery: Current Evidence and Suggestions for Advancing Future Research.Current obesity reports · 2025Review
- Lifestyle Medicine for Obesity in the Era of Highly Effective Anti-Obesity Treatment.Nutrients · 2025Review
- On the pathogenesis of obesity: causal models and missing pieces of the puzzle.Nature metabolism · 2024Review
- Impact of Chemotherapy Regimens on Body Composition of Breast Cancer Women: A Multicenter Study across Four Brazilian Regions.Nutrients · 2023Article
- The role of physical activity in the regulation of body weight: The overlooked contribution of light physical activity and sedentary behaviors.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023Review
- Associations of physical activity and sedentary behavior with appetite sensations and eating regulation behaviors before and during the initial year following bariatric surgery.Obesity science & practice · 2022Article
- Striking a balance: Orexigenic and energy-consuming effects of energy expenditure on body weight.Obesity (Silver Spring, Md.) · 2022Article
- Review
- Deciphering the constrained total energy expenditure model in humans by associating accelerometer-measured physical activity from wrist and hip.Scientific reports · 2021Article
- Physical Activity, Sleep, and Sedentary Behavior among Successful Long-Term Weight Loss Maintainers: Findings from a U.S. National Study.International journal of environmental research and public health · 2021Article
- Management of Childhood Obesity-Time to Shift from Generalized to Personalized Intervention Strategies.Nutrients · 2021Review
- Describing the Weight-Reduced State: Physiology, Behavior, and Interventions.Obesity (Silver Spring, Md.) · 2021Article
- The Fight Against Obesity Escalates: New Drugs on the Horizon and Metabolic Implications.Current obesity reports · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Long-term maintenance of weight loss requires sustained energy balance at the reduced body weight. This could be attained by coupling low total daily energy intake (TDEI) with low total daily energy expenditure (TDEE; low energy flux), or by pairing high TDEI with high TDEE (high energy flux). Within an environment characterized by high energy dense food and a lack of need for movement, it may be particularly difficult for weight-reduced individuals to maintain energy balance in a low flux state. Most of these individuals will increase body mass due to an inability to sustain the necessary level of food restriction. This increase in TDEI may lead to the re-establishment of high energy flux at or near the original body weight. We propose that following weight loss, increasing physical activity can effectively re-establish a state of high energy flux without significant weight regain. Although the effect of extremely high levels of physical activity on TDEE may be constrained by compensatory reductions in non-activity energy expenditure, moderate increases following weight loss may elevate energy flux and encourage physiological adaptations favorable to weight loss maintenance, including better appetite regulation. It may be time to recognize that few individuals are able to re-establish energy balance at a lower body weight without permanent increases in physical activity. Accordingly, there is an urgent need for more research to better understand the role of energy flux in long-term weight maintenance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.