ArticlePhysical review. E2019
Polarization wave at the onset of collective cell migration.
Article in Physical review. E, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Modelling the effect of cell motility on mixing and invasion in epithelial monolayers.Journal of biological physics · 2024Article
- PIEZO1 regulates leader cell formation and cellular coordination during collective keratinocyte migration.PLoS computational biology · 2024Article
- A hybrid model of intercellular tension and cell-matrix mechanical interactions in a multicellular geometry.Biomechanics and modeling in mechanobiology · 2020Article
- Multiscale modelling of motility wave propagation in cell migration.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Collective cell migration underlies morphogenesis, tissue regeneration, and cancer progression. How the biomechanical coupling between epithelial cells triggers and coordinates the collective migration is an open question. Here, we develop a one-dimensional model for an epithelial monolayer which predicts that after the onset of migration at an open boundary, cells in the bulk of the epithelium are gradually recruited into outward-directed motility, exhibiting traveling-wave-like behavior. We find an exact formula for the speed of this motility wave proportional to the square root of the cells' contractility, which accounts for cortex tension and adhesion between adjacent cells.
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Registered trials
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