Evidence map›Paper›PMID 31639371›Full record

ReviewAmerican journal of obstetrics and gynecology2020

From molecular to macro: the key role of the apical ligaments in uterovaginal support.

Caroline Kieserman-Shmokler, Carolyn W Swenson, Luyun Chen, Lisa M Desmond, James A Ashton-Miller, John O DeLancey

Abstract readReview
In one paragraph

Review in American journal of obstetrics and gynecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  7. Transcriptomic analysis revealsZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Vaginal tactile imaging: A review.Pelviperineology · 2023
    Article
  16. Article
  17. Article
  18. Biomechanical integrity score of the female pelvic floor.International urogynecology journal · 2022
    Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caroline Kieserman-ShmoklerUniversity of Michigan Departments of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI. Electronic address: ckieserm@med.umich.edu.
Carolyn W SwensonUniversity of Michigan Departments of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI.
Luyun ChenBiomedical Engineering, University of Michigan, Ann Arbor, MI.
Lisa M DesmondMountain Area Health Education Center, Asheville, NC.
James A Ashton-MillerMechanical Engineering, University of Michigan, Ann Arbor, MI.
John O DeLanceyUniversity of Michigan Departments of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI.

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
University of Michigan WRHR Career Development ProgramK12HD065257 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FENNER, DEE ELLEN · 2010 to 2019
$3.4M
NIA NIH HHS P30 AG024824NICHD NIH HHS K12 HD065257
6 · The paper itself

Abstract

To explain the pathophysiology of pelvic organ prolapse, we must first understand the complexities of the normal support structures of the uterus and vagina. In this review, we focus on the apical ligaments, which include the cardinal and uterosacral ligaments. The aims of this review are the following: (1) to provide an overview of the anatomy and histology of the ligaments; (2) to summarize the imaging and biomechanical studies of the ligament properties and the way they relate to anterior and posterior vaginal wall prolapse; and (3) to synthesize these findings into a conceptual model for the progression of prolapse.

Indexed as

Biomechanical PhenomenaFemaleHumansLigamentsPelvic FloorPelvic Organ Prolapseapical prolapseapical supportbiomechanicscardinal ligamentprolapseuterosacral ligamentvaginal apex

Identifiers

PMID31639371
PMCPMC7166152

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.