Evidence map›Paper›PMID 31639023›Full record

ArticleItalian journal of pediatrics2019

Practical tools to identify short children born small-for-gestational-age eligible for rhGH treatment according to Italian regulation.

Gianluca Tornese, Flavia Pricci, Maria Chiara Pellegrin, Marika Villa, Daniela Rotondi, Elvira Agazio, Egidio Barbi

Open access · goldAbstract readLetter
In one paragraph

Article in Italian journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gianluca TorneseInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy. gianluca.tornese@burlo.trieste.it.ORCID http://orcid.org/0000-0002-4395-3915
Flavia PricciDepartment Cardiovascular, endocrine-metabolic disease and aging, Istituto Superiore di Sanità, Rome, Italy.
Maria Chiara PellegrinInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
Marika VillaDepartment Cardiovascular, endocrine-metabolic disease and aging, Istituto Superiore di Sanità, Rome, Italy.
Daniela RotondiDepartment Cardiovascular, endocrine-metabolic disease and aging, Istituto Superiore di Sanità, Rome, Italy.
Elvira AgazioDepartment Cardiovascular, endocrine-metabolic disease and aging, Istituto Superiore di Sanità, Rome, Italy.
Egidio BarbiInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", Trieste, Italy.
Istituto Superiore di Sanità · ITIRCCS Materno Infantile Burlo Garofolo · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recombinant human growth hormone (rhGH) is an approved and effective treatment for short children born small for gestational age (SGA). Prevalence of children eligible for treatment as SGA is reported to be 1:1800. The latest data from the National Registry of Growth Hormone therapy (RNAOC) showed that the number of children treated with SGA indication is still small (prevalence 0.37/100,000) and these children are significantly less reported than those treated for growth hormone deficiency (GHD), although GHD prevalence is 1:4000-1:10,000. This means that many short children born SGA are still not properly identified, and therefore not treated with rhGH, or misdiagnosed as GHD. This article provides some practical tools for the identification of children eligible for rhGH treatment.

Indexed as

Body HeightInfant, Small for Gestational AgeChildChild, PreschoolFemaleHuman Growth HormoneHumansInfantInfant, NewbornItalyMalePractice Guidelines as TopicHuman Growth HormoneGrowth hormoneItalySmall for gestational age

Identifiers

PMID31639023
PMCPMC6805524
OpenAlexW2981644646

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.