Evidence map›Paper›PMID 31638966›Full record

ArticleBMC complementary and alternative medicine2019

Antioxidant and Cytoprotective effects of Pyrola decorata H. Andres and its five phenolic components.

Ban Chen, Xican Li, Jie Liu, Wei Qin, Minshi Liang, Qianru Liu, Dongfeng Chen

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ban ChenSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No.232, Guangzhou Higher Education Mega Center, Guangzhou, 510006, China.
Xican LiSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No.232, Guangzhou Higher Education Mega Center, Guangzhou, 510006, China. lixican@126.com.ORCID http://orcid.org/0000-0002-4358-3993
Jie LiuSchool of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Wei QinSchool of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Minshi LiangSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No.232, Guangzhou Higher Education Mega Center, Guangzhou, 510006, China.
Qianru LiuSchool of Chinese Herbal Medicine, Guangzhou University of Chinese Medicine, Waihuan East Road No.232, Guangzhou Higher Education Mega Center, Guangzhou, 510006, China.
Dongfeng ChenSchool of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China. chen888@gzucm.edu.cn.
Guangzhou University of Chinese Medicine · CN

Funding

Guangdong Science and Technology Project 2016A050503039National Nature Science Foundation of China 81573558National Nature Science Foundation of China 81673770
6 · The paper itself

Abstract

backgroundPyrola decorata H. Andres, is exclusively distributed in China and a source of traditional Chinese herbal medicine Luxiancao for more than 2000 years. Here, we evaluated the antioxidant and cytoprotective effects of P. decorata and its five phenolic components (protocatechuic acid, gallic acid, hyperoside, 2''-O-galloylhyperin, and quercetin), and discussed their antioxidant chemistry.

methodsA lyophilized aqueous extract of P. decorata (LAEP) was prepared and analyzed with high-performance liquid chromatography (HPLC). LAEP and its five phenolic components were comparatively investigated using five antioxidant assays, including ferric-reducing antioxidant power, cupric ion-reducing antioxidant capacity, 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide radical (PTIO

resultsIn the five antioxidant assays, LAEP and its five phenolic components dose-dependently increased the radical-scavenging (or reducing power) activities. However, the IC

conclusionLAEP and its five phenolic components may undergo redox-based pathways (such as electron transfer and H

Indexed as

AntioxidantsCell LineCell SurvivalChinaChromatography, High Pressure LiquidDrugs, Chinese HerbalHumansMolecular StructurePhenolsProtective AgentsPyrolaTandem Mass SpectrometryAntioxidantsDrugs, Chinese HerbalPhenolsProtective Agents2′′-O-galloylhyperinAntioxidantCytoprotectionHyperosideLuxiancaoMesenchymal stem cellsPyrola decorata

Identifiers

PMID31638966
PMCPMC6805648
OpenAlexW2980691534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.