Evidence map›Paper›PMID 31638403›Full record

ArticleOrganic letters2019

A Redox Isomerization Strategy for Accessing Modular Azobenzene Photoswitches with Near Quantitative Bidirectional Photoconversion.

Jie S Zhu, Julio M Larach, Robert J Tombari, Phillip W Gingrich, Stanley R Bode, Jeremy R Tuck, Hunter T Warren, Jung-Ho Son, Whitney C Duim, James C Fettinger and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jie S ZhuDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.ORCID 0000-0003-3009-4135
Julio M LarachDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Robert J TombariDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Phillip W GingrichDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Stanley R BodeDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Jeremy R TuckDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Hunter T WarrenDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Jung-Ho SonDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
Whitney C DuimDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.
James C FettingerDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.ORCID 0000-0002-6428-4909
Makhluf J HaddadinDepartment of Chemistry , American University of Beirut , Beirut 1107 2020 , Lebanon.
Dean J TantilloDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.ORCID 0000-0002-2992-8844
Mark J KurthDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.ORCID 0000-0001-8496-6125
David E OlsonDepartment of Chemistry , University of California, Davis , One Shields Avenue , Davis , California 95616 , United States.ORCID 0000-0002-4517-0543

Funding

SynthesisP30DK072517 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VERKMAN, ALAN S · 2005 to 2022
$18.1M
XENOBIOTICS AND PRIMARY BILIARY CIRRHOSISR01DK067003 · NIDDK · UNIVERSITY OF CALIFORNIA DAVIS · PI GERSHWIN, MERRILL E · 2003 to 2017
$4.4M
Design, Synthesis, and Evaluation of Neural Plasticity-Promoting Analogs of Iboga and Ergoline AlkaloidsR01GM128997 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI OLSON, DAVID E · 2018 to 2022
$1.8M
Mechanistically based therapeutic strategies in murine primary biliary cholangitisR01DK123262 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GERSHWIN, MERRILL E · 2020 to 2023
$1.6M
UC Davis Training Program in Chemical BiologyT32GM113770 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BEAL, PETER A. · 2015 to 2019
$742k
NIDDK NIH HHS P30 DK072517NIDDK NIH HHS R01 DK067003NIDDK NIH HHS R01 DK123262NIGMS NIH HHS R01 GM128997NIGMS NIH HHS T32 GM113770
6 · The paper itself

Abstract

Photoswitches capable of accessing two geometric states are highly desirable, especially if their design is modular and incorporates a pharmacophore tethering site. We describe a redox isomerization strategy for synthesizing

Indexed as

Photochemical ProcessesAzo CompoundsDimethyl SulfoxideIsomerismModels, MolecularMolecular ConformationOxidation-ReductionazobenzeneAzo CompoundsDimethyl Sulfoxide

Identifiers

PMID31638403
PMCPMC7158698

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.