ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2019
A retrospective study of patients with blood culture-confirmed typhoid fever in Fiji during 2014-2015: epidemiology, clinical features, treatment and outcome.
Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Pooled it
- A Systematic Review on Antimicrobial Resistance amongThe American journal of tropical medicine and hygiene · 2020Pooled it
- Burden of typhoid fever in primary and hospital care in Indonesia: a serial cross-sectional study using national health insurance (BPJS Kesehatan) data, 2015-2023.The Lancet regional health. Western Pacific · 2026Article
- Emergence of azithromycin and ciprofloxacin non-susceptible genotype 4.2.2Antimicrobial agents and chemotherapy · 2025Article
- Human leptospirosis in the central division of Fiji: a retrospective epidemiological study.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2025Article
- Genetic heterogeneity in theMicrobial genomics · 2024Article
- Typhoid Control in an Era of Antimicrobial Resistance: Challenges and Opportunities.Open forum infectious diseases · 2023Article
- Genomic epidemiology ofThe Lancet regional health. Western Pacific · 2022Article
- Sepsis and disseminated intravascular coagulation are rare complications of typhoid fever: A case report.Annals of medicine and surgery (2012) · 2022Article
- Typhoid fever in travellers: estimating the risk of acquisition by country.Journal of travel medicine · 2021Article
- Assessment of Rapid Diagnostic Tests for Typhoid Diagnosis and Assessment of Febrile Illness Outbreaks in Fiji.The American journal of tropical medicine and hygiene · 2021Article
- Genotype Diversity before and after the Introduction of a Rotavirus Vaccine into the National Immunisation Program in Fiji.Pathogens (Basel, Switzerland) · 2021Article
- Hospitalization of Pediatric Enteric Fever Cases, Dhaka, Bangladesh, 2017-2019: Incidence and Risk Factors.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
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Authors and funding
8 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTyphoid fever is endemic in Fiji. We sought to describe the epidemiology, clinical features and case fatality risk of blood culture-confirmed typhoid fever from January 2014 through December 2015.
methodsBlood culture-positive patients were identified from a typhoid surveillance line list. A standardised case investigation form was used to record data from patients' medical records.
resultsOf 542 patients, 518 (95.6%) were indigenous Fijians (iTaukei) and 285 (52.6%) were male. The median (IQR) age was 25 (16-38) y. Mean (SD) time from the onset of illness to admission was 11.1 (6.9) d. Of 365 patients with clinical information, 346 (96.9%) had fever, 239 (66.9%) diarrhoea, 113 (33.5%) vomiting, and 72 (30.2%) abdominal pain. There were 40 (11.0%) patients with complications, including 17 (4.7%) with shock, and 11 (3.0%) with hepatitis. Nine patients died for a case fatality risk of 1.7%. Of the 544 Salmonella Typhi isolates tested, none were resistant to first line antimicrobials; 3(0.8%) were resistant to ciprofloxacin and 5(1.4%) to nalidixic acid.
conclusionsIn Fiji, most blood culture-confirmed typhoid fever cases were in young adults. Common clinical manifestations were fever and gastrointestinal symptoms. Further studies are required to elucidate the factors associated with complications and death.
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