Evidence map›Paper›PMID 31638047›Full record

ArticleIndian journal of ophthalmology2019

Evaluation of choroidal hyperreflective dots in acute and chronic central serous chorioretinopathy.

Daren Hanumunthadu, Alexandre Matet, Mohammed Abdul Rasheed, Abhilash Goud, Kiran Kumar Vuppurabina, Jay Chhablani

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Hyperreflective Choroidal Foci: A Comprehensive Review.Journal of ophthalmic & vision research · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Choroidal vascular alterations evaluated by ultra-widefield indocyanine green angiography in central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
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  8. Article
  9. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Daren HanumunthaduMoorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.
Alexandre MatetInstitut Curie, PSL Research University, Ophthalmology Department; and Université Paris Descartes, Paris, France.
Mohammed Abdul RasheedSrimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.
Abhilash GoudSrimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.
Kiran Kumar VuppurabinaSrimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.
Jay ChhablaniSrimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.
Moorfields Eye Hospital NHS Foundation Trust · GBDélégation Paris 5 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To determine the association between hyperreflective dots (HRD) in the choroid and visual acuity and swept-source optical coherence tomography (SS-OCT)-derived structural parameters in central serous chorioretinopathy (CSC). Methods: SS-OCT images (single visit) of consecutive patients with CSC were evaluated for the presence of HRDs in the choroid using an automated algorithm and manual measurements of central macular and subfoveal choroidal thicknesses were obtained. Results: 61 eyes of 61 subjects were included in this retrospective study (32 subjects with acute and 29 with chronic CSC). Mean (± SD) choroidal HRD counts in acute and chronic CSC were 139.4 ± 29.9 and 124.9 ± 28.1, respectively (P = 0.04). In acute CSC, HRD was correlated with both age (P = 0.004) and subfoveal choroidal thickness (SFCT) (P = 0.016), but not with visual acuity or other OCT-derived measurements. In chronic CSC, HRD was correlated with central macular thickness (P = 0.011); neurosensory detachment height (P = 0.046); SFCT (P = 0.012). Considering all patients, the presence of HRDS was significantly negatively correlated with age (r = -0.401; P= 0.002) and SFCT (r = -0.332; P= 0.010). Conclusion: HRDs are correlated with both age and SFCT in acute CSC, and with CMT, height of neurosensory detachment and SFCT in chronic CSC. Development of HRDS is associated with the remodelling of chorioretinal structures as previously noted in CSC.

Indexed as

Visual AcuityAdultCentral Serous ChorioretinopathyChoroidChronic DiseaseDisease ProgressionFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexTomography, Optical CoherenceCentral serous chorioretinopathychoroidhyperreflective dotsoptical coherence tomography

Identifiers

PMID31638047
PMCPMC6836603
OpenAlexW2982086288

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.