ArticleeLife2019
An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 38 citations in OpenAlex.
- Hepatic Mechanisms and Therapeutic Target Underpinning Hypercoagulation in Obesity: Insights From Genetic and Transcriptomic Analyses.Exploration (Beijing, China) · 2026Article
- Mycobacterium tuberculosis infects human peripheral hematopoietic multipotent progenitors and promotes their myeloid differentiation in vitro.Cell death & disease · 2026Article
- Context-specific roles for IL-17 in tuberculosis.PLoS pathogens · 2026Review
- Deciphering lung granulomas in HIV & TB co-infection: unveiling macrophages aggregation with IL6R/STAT3 activation.Emerging microbes & infections · 2024Article
- A modified multiple-criteria decision-making approach based on a protein-protein interaction network to diagnose latent tuberculosis.BMC medical informatics and decision making · 2024Article
- ISG15/USP18/STAT2 is a molecular hub regulating IFN I-mediated control of Dengue and Zika virus replication.Frontiers in immunology · 2024Article
- The Endogenous Retinoic Acid Receptor Pathway Is Exploited by Mycobacterium tuberculosis during Infection, Both In Vitro and In Vivo.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- C/EBPβ/AEP Signaling Drives Alzheimer's Disease Pathogenesis.Neuroscience bulletin · 2023Review
- Autophagic reprogramming of bone marrow-derived macrophages.Immunologic research · 2023Article
- Genomic evidence for adaptation to tuberculosis in the Andes before European contact.iScience · 2023Article
- Altered IL-6 signalling and risk of tuberculosis disease: a meta-analysis and Mendelian randomisation study.medRxiv : the preprint server for health sciences · 2023Article
- High seroprevalence of Leishmania infantum is linked to immune activation in people with HIV: a two-stage cross-sectional study in Bahia, Brazil.Frontiers in microbiology · 2023Article
- Early innate cell interactions withFrontiers in immunology · 2023Review
- Long-term hematopoietic stem cells as a parasite niche during treatment failure in visceral leishmaniasis.Communications biology · 2022Article
- Cell specific peripheral immune responses predict survival in critical COVID-19 patients.Nature communications · 2022Article
- Cytokine Receptors-Regulators of Antimycobacterial Immune Response.International journal of molecular sciences · 2022Review
- Dysregulated expression of microRNAs in aqueous humor from intraocular tuberculosis patients.Molecular biology reports · 2022Article
- Various theranostics and immunization strategies based on nanotechnology against Covid-19 pandemic: An interdisciplinary view.Life sciences · 2021Review
- Exaggerated IL-17A activity in human in vivo recall responses discriminates active tuberculosis from latent infection and cured disease.Science translational medicine · 2021Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 5 institutions in 3 countries.
Murilo DelgoboLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Daniel Agb MendesLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Edgar KozlovaLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Edroaldo Lummertz RochaLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Gabriela F Rodrigues-LuizLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Lucas MascarinLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Greicy DiasLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Daniel O PatrícioLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Tim DierckxDepartment of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven, Leuven, Belgium.
Maíra A BiccaLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Gaëlle BrettonLaboratory of Molecular Immunology, The Rockefeller University, New York, United States.
Yonne Karoline Tenório de MenezesLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Márick R StarickLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Darcita RovarisLaboratório Central do Estado de Santa Catarina/LACEN, Florianópolis, Brazil.
Joanita Del MoralServiço de Hematologia, Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Daniel S MansurLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.
Johan Van WeyenberghDepartment of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory for Clinical and Epidemiological Virology, KU Leuven, Leuven, Belgium.
André BáficaLaboratório de Imunobiologia, Departmento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de Santa Catarina, Florianópolis, Brazil.ORCID 0000-0002-5148-600X
Universidade Federal de Santa Catarina · BRRega Institute for Medical Research · BEBoston University · USFundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina · BRRockefeller University · US
Funding
Mechanisms by which M. tuberculosis 13KDa lectin modulates human immune responsesR01TW008276 · FIC · FEDERAL UNIVERSITY OF SANTA CATARINA · PI BAFICA, ANDRE · 2009 to 2014
$261kCAPES 23038.010048/2013-27Conselho Nacional de Desenvolvimento Científico e Tecnológico PQCoordenação de Aperfeiçoamento de Pessoal de Nível Superior 23038.010048/2013-27FIC NIH HHS R01 TW008276Fonds Wetenschappelijk Onderzoek G0D6817NFonds Wetenschappelijk Onderzoek VLAIO IWT141614FWO G0D6817NHoward Hughes Medical Institute Early Career Scientist 55007412NIH HHS Global Research Initiative Program TW008276
Abstract
Monocyte counts are increased during human tuberculosis (TB) but it has not been determined whether
Indexed as
Antigens, CD34CCAAT-Enhancer-Binding ProteinsCell DifferentiationCell ProliferationCytokinesGenome-Wide Association StudyHumansHydrolasesInterferonsInterleukin-6MacrophagesMonocytesMycobacterium tuberculosisMyeloid CellsProteomicsReceptors, Interleukin-6Antigens, CD34CCAAT-Enhancer-Binding ProteinsCytokinesHsaD protein, Mycobacterium tuberculosisHydrolasesInterferonsInterleukin-6Receptors, Interleukin-6computational biologyevolutionhumanimmunologyinflammationinterferonsinterleukinsMycobacteriumsystems biologytuberculosis
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.