SynthesisMultiple sclerosis (Houndmills, Basingstoke, England)2019
Computerized neuropsychological assessment devices in multiple sclerosis: A systematic review.
Synthesis in Multiple sclerosis (Houndmills, Basingstoke, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04604041 (Investigation of Subclinical Markers of Multiple Sclerosis), which is not on this map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of Subclinical Markers of Multiple Sclerosis
Who cites it
26 citing papers in PubMed.
- Strategies for integrating artificial intelligence and cognitive assessment to predict disability progression in relapsing-remitting multiple sclerosis: A model development study.PLOS digital health · 2026Article
- Remote, self-administered, smartphone cognitive testing in a registry-based cohort: Feasibility, reliability, and validity findings.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Monitoring cognition in multiple sclerosis via adaptive smartphone games-first insights from a validation study.Frontiers in digital health · 2026Article
- Remote, self-administered, smartphone cognitive testing in a registry-based cohort: Feasibility, reliability, and validity findings.medRxiv : the preprint server for health sciences · 2025Article
- Review
- Large-scale online assessment uncovers a distinct Multiple Sclerosis subtype with selective cognitive impairment.Nature communications · 2025Article
- Development of the KeyStrokes test: An online neuropsychological assessment for attention, processing speed and executive function.Journal of neuropsychology · 2025Article
- Sensitivity and Specificity of a Revised Version of the TRACK-MS Screening Battery for Early Detection of Cognitive Impairment in Patients with Multiple Sclerosis.Biomedicines · 2025Article
- Plateau of practice effects and noise with repeat SDMT testing in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2025Article
- Addressing cortex dysregulation in youth through brain health check coaching and prophylactic brain development.INNOSC theranostics & pharmacological sciences · 2024Article
- Novel computerized neurocognitive test battery is sensitive to cancer-related cognitive deficits in survivors.Journal of cancer survivorship : research and practice · 2024Article
- Neuropsychological assessment in MS is outdated and in need for innovation: NO.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024Article
- Computerized Cognitive Test Batteries for Children and Adolescents-A Scoping Review of Tools For Lab- and Web-Based Settings From 2000 to 2021.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2023Article
- Cognitive impairment in multiple sclerosis: "classic" knowledge and recent acquisitions.Arquivos de neuro-psiquiatria · 2023Article
- Utility of Diffusion Modeling of Cogstate Brief Battery Test Performance in Detecting Mild Cognitive Impairment.Assessment · 2023Article
- Review
- Cognitive Rehabilitation in Multiple Sclerosis in the Period from 2013 and 2021: A Narrative Review.Brain sciences · 2021Review
- Validity of Digital Assessments in Screening for HIV-Related Cognitive Impairment: a Review.Current HIV/AIDS reports · 2021Review
- Digital Biomarkers in Multiple Sclerosis.Brain sciences · 2021Review
- A validation study for remote testing of cognitive function in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe proliferation of computerized neuropsychological assessment devices (CNADs) for screening and monitoring cognitive impairment is increasing exponentially. Previous reviews of computerized tests for multiple sclerosis (MS) were primarily qualitative and did not rigorously compare CNADs on psychometric properties.
objectiveWe aimed to systematically review the literature on the use of CNADs in MS and identify test batteries and single tests with good evidence for reliability and validity.
methodA search of four major online databases was conducted for publications related to computerized testing and MS. Test-retest reliability and validity coefficients and effect sizes were recorded for each CNAD test, along with administration characteristics.
resultsWe identified 11 batteries and 33 individual tests from 120 peer-reviewed articles meeting the inclusion criteria. CNADs with the strongest psychometric support include the CogState Brief Battery, Cognitive Drug Research Battery, NeuroTrax, CNS-Vital Signs, and computer-based administrations of the Symbol Digit Modalities Test.
conclusionWe identified several CNADs that are valid to screen for MS-related cognitive impairment, or to supplement full, conventional neuropsychological assessment. The necessity of testing with a technician, and in a controlled clinic/laboratory environment, remains uncertain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.