ArticleChemistry (Weinheim an der Bergstrasse, Germany)2020
Cyclotriphosphate: A Brief History, Recent Developments, and Perspectives in Synthesis.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Bio-inspired multifunctional disruptors of calcium oxalate crystallization.Nature communications · 2025Article
- Direct conversion of various phosphate sources to a versatile P-X reagent [TBA][PONature communications · 2025Article
- Heat flows solubilize apatite to boost phosphate availability for prebiotic chemistry.Nature communications · 2025Article
- Synthesis and Properties of α-Phosphate-Modified Nucleoside Triphosphates.Molecules (Basel, Switzerland) · 2024Review
- Pentaphosphorylation via the Anhydride of Dihydrogen Pentametaphosphate: Access to Nucleoside Hexa- and Heptaphosphates and Study of Their Interaction with Ribonuclease A.ACS central science · 2024Article
- Stabilized Molecular Diphosphorus Pentoxide, PJournal of the American Chemical Society · 2023Article
- Building the uracil skeleton in primitive ponds at the origins of life: carbamoylation of aspartic acid.Scientific reports · 2022Article
- Inorganic Polymeric Materials for Injured Tissue Repair: Biocatalytic Formation and Exploitation.Biomedicines · 2022Review
- Carbamoyl phosphate and its substitutes for the uracil synthesis in origins of life scenarios.Scientific reports · 2021Article
- The chemistry of branched condensed phosphates.Nature communications · 2021Article
- Synthesis of α,δ-Disubstituted Tetraphosphates and Terminally-Functionalized Nucleoside Pentaphosphates.Journal of the American Chemical Society · 2021Article
- Four Phosphates at One Blow: Access to Pentaphosphorylated Magic Spot Nucleotides and Their Analysis by Capillary Electrophoresis.The Journal of organic chemistry · 2020Article
- Bacterial Phosphate Granules Contain Cyclic Polyphosphates: Evidence fromJournal of the American Chemical Society · 2020Article
- Let's Make White Phosphorus Obsolete.ACS central science · 2020Review
- Cyclotriphosphate: A Brief History, Recent Developments, and Perspectives in Synthesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Synthetic Strategies for Dinucleotides Synthesis.Molecules (Basel, Switzerland) · 2019Review
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4 authors.
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Abstract
There has been a recent upsurge in the study and application of approaches utilizing cyclotriphosphate 1 (cyclo-TP, also known as trimetaphosphate, TMP) and/or proceeding through its analogues in synthetic chemistry to access modified oligo- and polyphosphates. This is especially useful in the area of chemical nucleotide synthesis, but by no means restricted to it. Enabled by new high yielding and easy-to-implement methodologies, these approaches promise to open up an area of research that has previously been underappreciated. Additionally, refinements of concepts of prebiotic phosphorylation chemistry have been disclosed that ultimately rely on cyclo-TP 1 as a precursor, placing it as a potentially central compound in the emergence of life. Given the importance of such concepts for our understanding of prebiotic chemistry in combination with the need to readily access modified polyphosphates for structural and biological studies, this paper will discuss selected recent developments in the field of cyclo-TP chemistry, briefly touch on ultraphosphate chemistry, and highlight areas in which further developments can be expected.
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