ReviewJournal of neural transmission (Vienna, Austria : 1996)2020
Neurostimulation methods in the treatment of chronic pain.
Review in Journal of neural transmission (Vienna, Austria : 1996), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06009159 (Vagus Nerve Stimulation), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vagus Nerve Stimulation(VNS) As Treatment For Fibromyalgia Patients
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Neuromodulation techniques for acute and preventive migraine treatment: a systematic review and meta-analysis of randomized controlled trials.The journal of headache and pain · 2020Pooled it
- Non-invasive neuromodulation effects on painful diabetic peripheral neuropathy: a systematic review and meta-analysis.Scientific reports · 2020Pooled it
- Fibromyalgia: an update on clinical characteristics, aetiopathogenesis and treatment.Nature reviews. Rheumatology · 2020Pooled it
- Hunyuan zhuang improves interoception: evidence from an expert-novice study and a pilot randomized controlled trial.Scientific reports · 2026Trial
- Comparative Analysis of Psychophysiological Responses in Fibromyalgia Patients: Evaluating Neuromodulation Alone, Neuromodulation Combined with Virtual Reality, and Exercise Interventions.Medicina (Kaunas, Lithuania) · 2024Trial
- Chronic Ocular Surface Pain: A Missing Member of the Chronic Overlapping Pain Conditions?Drugs · 2026Review
- Pain Medicine Specialist: Championing High-Quality Development for Neuromodulation Technology.Current medical science · 2026Review
- Electrotherapy in the management of neuropathic corneal pain: narrative review.Experimental biology and medicine (Maywood, N.J.) · 2026Review
- Review
- An update on non-pharmacological interventions for pain relief.Cell reports. Medicine · 2025Review
- Case Report: Peripheral combined central dual-target magnetic stimulation for non- motor symptoms of Parkinson's disease.Frontiers in psychiatry · 2025Article
- Electroceuticals: Unlocking the promise of therapies.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024Review
- Transcutaneous vagus nerve stimulation effects on chronic pain: systematic review and meta-analysis.Pain reports · 2024Review
- Assessment of decision-making autonomy in chronic pain patients: a pilot study.BMC medical ethics · 2024Article
- [Spinal cord stimulation in refractory complex regional pain syndrome. A prospective study].Revista de neurologia · 2024Article
- Comparative Efficacy of Neuromodulation and Structured Exercise Program on Autonomic Modulation in Fibromyalgia Patients: Pilot Study.Journal of clinical medicine · 2024Article
- Comparative Analysis of Ventilatory Responses during Stress Tests in Patients with Chronic Pain: Implications for Therapeutic Interventions.Journal of functional morphology and kinesiology · 2024Article
- Innovation at the Intersection: Emerging Translational Research in Neurology and Psychiatry.Cells · 2024Article
- Anatomo-physiological basis and applied techniques of electrical neuromodulation in chronic pain.Journal of anesthesia, analgesia and critical care · 2024Review
- Hydrogels in wearable neural interfaces.Med-X · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The goal of this narrative review was to give an up-to-date overview of the peripheral and central neurostimulation methods that can be used to treat chronic pain. Special focus has been given to three pain conditions: neuropathic pain, nociplastic pain and primary headaches. Both non-invasive and invasive techniques are briefly presented together with their pain relief potentials. For non-invasive stimulation techniques, data concerning transcutaneous electrical nerve stimulation (TENS), transcranial direct current stimulation (tDCS), repetitive transcranial magnetic stimulation (rTMS), remote electrical neuromodulation (REN) and vagus nerve stimulation (VNS) are provided. Concerning invasive stimulation techniques, occipital nerve stimulation (ONS), vagus nerve stimulation (VNS), epidural motor cortex stimulation (EMCS), spinal cord stimulation (SCS) and deep brain stimulation (DBS) are presented. The action mode of all these techniques is only partly understood but can be very different from one technique to the other. Patients' selection is still a challenge. Recent consensus-based guidelines for clinical practice are presented when available. The development of closed-loop devices could be of interest in the future, although the clinical benefit over open loop is not proven yet.
Indexed as
Identifiers
31637517What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.