Evidence map›Paper›PMID 31637515›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Patterns of pain medication use associated with reported pain interference in older adults with and without cancer.

Amy J Davidoff, Maureen E Canavan, Shelli Feder, Shiyi Wang, Ella Sheinfeld, Erin E Kent, Jennifer Kapo, Carolyn J Presley

Open access · greenAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Amy J DavidoffYale School of Public Health, New Haven, CT, USA. Amy.Davidoff@Yale.Edu.ORCID http://orcid.org/0000-0001-8141-9249
Maureen E CanavanYale Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale School of Medicine, New Haven, CT, USA.
Shelli FederYale National Clinical Scholars Program, Yale School of Medicine, New Haven, CT, USA.
Shiyi WangYale School of Public Health, New Haven, CT, USA.
Ella SheinfeldYale Fox Fellowship, New Haven, CT, USA.
Erin E KentNational Cancer Institute, Bethesda, MD, Fairfax, VA, USA.
Jennifer KapoYale Cancer Center, New Haven, CT, USA.
Carolyn J PresleyThe Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Yale Cancer Center · USNational Cancer Institute · USTel Aviv University · ILThe Ohio State University · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Translational Training Grant in Experimental TherapeuticsK12CA133250 · NCI · OHIO STATE UNIVERSITY · PI WILLIAM E. CARSON, Rosa Lapalombella · 2008 to 2026
$15.0M
Yale University Clinical and Translational Science Award ProgramKL2TR000140 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$2.9M
NCATS NIH HHS KL2 TR000140NCATS NIH HHS UL1 TR001863NCI NIH HHS Contract HHSN261201700690PNCI NIH HHS K12 CA133250
6 · The paper itself

Abstract

contextConcerns about the adequacy of pain management among older adults are increasing, particularly with restrictions on opioid prescribing.

objectivesTo examine associations between prescription pain medication receipt and patient-reported pain interference in older adults with and without cancer.

methodsUsing the 2007-2012 Surveillance Epidemiology and End Results (SEER)-Medicare Health Outcomes Survey (MHOS) database linked to Medicare Part D prescription claims, we selected MHOS respondents (N = 15,624) aged ≥ 66 years, ≤ 5 years of a cancer diagnosis (N = 9105), or without cancer (N = 6519). We measured receipt of opioids, non-steroidal anti-inflammatory drugs, and antiepileptics, and selected antidepressants within 30 days prior to survey. Patient-reported activity limitation due to pain (pain interference) within the past 30 days was summarized as severe, moderate, or mild/none. Logistic regression using predictive margins estimated associations between pain interference, cancer history, and pain medication receipt, adjusting for socio-demographics, chronic conditions, and Part D low-income subsidy.

resultsSevere or moderate pain interference was reported by 21.3% and 46.1%, respectively. Pain medication was received by 21.5%, with 11.6% receiving opioids. Among adults reporting severe pain interference, opioid prescriptions were filled by 27.0% versus 23.8% (p = 0.040) with and without cancer, respectively. Over half (56%) of adults reporting severe pain in both groups failed to receive any prescription pain medication.

conclusionsOlder adults with cancer were more likely to receive prescription pain medications compared with adults without cancer; however, many older adults reporting severe pain interference did not receive medications. Improved assessment and management of pain among older adults with and without cancer is urgently needed.

Indexed as

AgedAged, 80 and overAge FactorsAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalCancer PainDrug PrescriptionsFemaleHumansMaleMedicare Part DNeoplasmsPainPractice Patterns, Physicians'SEER ProgramUnited StatesAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalCancerMedicare health outcomes studyMedicare part DOpioidsPain interferencePain treatment

Identifiers

PMID31637515
PMCPMC7338979
OpenAlexW2981892684

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.