Evidence map›Paper›PMID 31637329›Full record

ArticlePathogens & immunity2019

Impact of Reduced Fluoroquinolone Use on

Sarah N Redmond, Sandra Y Silva, Brigid M Wilson, Jennifer L Cadnum, Curtis J Donskey

Open access · diamondAbstract read
In one paragraph

Article in Pathogens & immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Global, regional, and national burden of Clostridioides difficile infection (1990-2021) with projections to 2051: A multimodal analysis integrating machine learning (SHAP-XGBoost) and GBD 2021 data.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Review
  4. Microbiology spectrum · 2026
    Article
  5. Review
  6. Article
  7. The fitness connection of antibiotic resistance.Frontiers in microbiology · 2025
    Article
  8. Epidemiology ofAntimicrobial agents and chemotherapy · 2024
    Article
  9. Article
  10. Strategies to preventInfection control and hospital epidemiology · 2023
    Article
  11. Incidence and Risk Factors forMicroorganisms · 2023
    Article
  12. Article
  13. Association between Antibiotic Use and Hospital-OnsetAntibiotics (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Sarah N RedmondCase Western Reserve University School of Medicine; Cleveland, Ohio.
Sandra Y SilvaClinical and Translational Science Program; School of Medicine; Case Western Reserve University; Cleveland, Ohio.
Brigid M WilsonGeriatric Research, Education, and Clinical Center; Louis Stokes Cleveland VA Medical Center; Cleveland, Ohio.
Jennifer L CadnumResearch Service; Louis Stokes Cleveland VA Medical Center; Cleveland, Ohio.
Curtis J DonskeyCase Western Reserve University School of Medicine; Cleveland, Ohio.
Geriatric Research Education and Clinical Center · USCase Western Reserve University · USLouis Stokes Cleveland VA Medical Center · USUniversity School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFluoroquinolone restriction has been proposed as a control measure for

methodsIn a hospital and affiliated long-term care facility (LTCF), antimicrobial stewardship and environmental cleaning interventions were implemented between 2009 and 2018, and

resultsBetween 2009 and 2018, prescribing of fluoroquinolones to inpatients decreased by 43%, coinciding with significant reductions in the healthcare-associated CDI rates in the hospital and LTCF and a decline in the percentage of

conclusionOur results provide support for fluoroquinolone restriction as a control measure for CDI outbreaks due to fluoroquinolone-resistant 027 strains, but also highlight the need for randomized trials as factors such as reduction in other antibiotic classes and improved cleaning may also impact CDI rates.

Indexed as

antimicrobial stewardshipClostridioides difficileenvironmentfluoroquinolonelong-term care facility

Identifiers

PMID31637329
PMCPMC6782113
OpenAlexW2979224172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.