Evidence map›Paper›PMID 31637298›Full record

ArticleLaryngoscope investigative otolaryngology2019

Engineered oncolytic virus for the treatment of cholesteatoma: A pilot in vivo study.

Ravi N Samy, Brian R Earl, Noga Lipschitz, Ivy Schweinzger, Mark Currier, Timothy Cripe

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ravi N SamyDepartment of Otolaryngology-Head and Neck Surgery University of Cincinnati College of Medicine Cincinnati Ohio U.S.A.ORCID https://orcid.org/0000-0002-5580-3455
Brian R EarlDepartment of Otolaryngology-Head and Neck Surgery University of Cincinnati College of Medicine Cincinnati Ohio U.S.A.
Noga LipschitzDepartment of Otolaryngology-Head and Neck Surgery University of Cincinnati College of Medicine Cincinnati Ohio U.S.A.ORCID https://orcid.org/0000-0002-1252-8641
Ivy SchweinzgerDepartment of Communication Sciences and Disorders University of Cincinnati College of Allied Health Sciences Cincinnati Ohio U.S.A.
Mark CurrierCenter for Childhood Cancer and Blood Diseases The Research Institute at Nationwide Children's Hospital Columbus Ohio U.S.A.
Timothy CripeCenter for Childhood Cancer and Blood Diseases The Research Institute at Nationwide Children's Hospital Columbus Ohio U.S.A.
University of Cincinnati Medical Center · USNationwide Children's Hospital · USCincinnati Children's Hospital Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDetermine if oncolytic herpes simplex virus (oHSV) can eradicate cholesteatoma (CHST) in a gerbil model.

methodsAn in vivo model of CHST was developed in Mongolian gerbils by combining

resultsThe

conclusionsLEVEL OF EVIDENCE: NA.

Indexed as

CholesteatomaoHSVoncolytic virotherapy

Identifiers

PMID31637298
PMCPMC6793611
OpenAlexW2980755466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.