ArticleEvolution letters2019
Tightly linked antagonistic-effect loci underlie polygenic phenotypic variation in
Article in Evolution letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Correlations between causal effect sizes of proximal SNPs vary with functional annotations and implicate stabilizing selection.Nature genetics · 2026Article
- Natural variation suggests candidate genes underlying Caenorhabditis elegans susceptibility to diverse toxicants.Toxicological sciences : an official journal of the Society of Toxicology · 2026Article
- High-Throughput Toxicity Screening withEnvironmental science & technology · 2026Review
- Natural variation suggests candidate genes underlyingbioRxiv : the preprint server for biology · 2025Article
- Ecological stoichiometry and life history theory, not the identity of genomic variants, predict rapid adaptation.bioRxiv : the preprint server for biology · 2025Article
- The regulatory architecture of gene expression variation in Caenorhabditis elegans revealed by multi-strain allele-specific analysis.Genetics · 2025Article
- Article
- The regulatory architecture of gene expression variation inbioRxiv : the preprint server for biology · 2025Article
- Life history in Caenorhabditis elegans: from molecular genetics to evolutionary ecology.Genetics · 2024Review
- Natural variation in infection specificity of Caenorhabditis briggsae isolates by two RNA viruses.PLoS pathogens · 2024Article
- Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection.Research square · 2023Article
- Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection.medRxiv : the preprint server for health sciences · 2023Article
- Higher-order epistasis shapes natural variation in germ stem cell niche activity.Nature communications · 2023Article
- Phenotypic stasis with genetic divergence.Peer community journal · 2023Article
- Linkage mapping reveals loci that underlie differences in Caenorhabditis elegans growth.G3 (Bethesda, Md.) · 2022Article
- Article
- Gene regulation in Escherichia coli is commonly selected for both high plasticity and low noise.Nature ecology & evolution · 2022Article
- Slow Recovery from Inbreeding Depression Generated by the Complex Genetic Architecture of Segregating Deleterious Mutations.Molecular biology and evolution · 2022Article
- Article
- Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Recent work has provided strong empirical support for the classic polygenic model for trait variation. Population-based findings suggest that most regions of genome harbor variation affecting most traits. Here, we use the approach of experimental genetics to show that, indeed, most genomic regions carry variants with detectable effects on growth and reproduction in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.