Evidence map›Paper›PMID 31636762›Full record

ArticleHereditary cancer in clinical practice2019

Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report.

Mev Dominguez-Valentin, Toni T Seppälä, Julian R Sampson, Finlay Macrae, Ingrid Winship, D Gareth Evans, Rodney J Scott, John Burn, Gabriela Möslein, Inge Bernstein and 33 more

Abstract read
In one paragraph

Article in Hereditary cancer in clinical practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Modifier genes and Lynch syndrome: some considerations.Hereditary cancer in clinical practice · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. Immunology of Lynch Syndrome.Current oncology reports · 2021
    Review
  16. Article
  17. COVID-19 Disruptions to Endoscopic Surveillance in Lynch Syndrome.Cancer prevention research (Philadelphia, Pa.) · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors.

Mev Dominguez-Valentin *1Department of Tumor Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway.ORCID 0000-0001-7856-0057
Toni T Seppälä *2Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Helsinki, Finland.
Julian R Sampson4Division of Cancer and Genetics, Institute of Medical Genetics, Cardiff University School of Medicine, Cardiff, UK.
Finlay Macrae5The Royal Melbourne Hospital, Melbourne, Australia.
Ingrid Winship5The Royal Melbourne Hospital, Melbourne, Australia.
D Gareth Evans7University of Manchester & Manchester University Hospitals Foundation Trust, Manchester, UK.
Rodney J ScottUniversity of Newcastle and the Hunter Medical Research Institute, Callaghan, Australia.
John Burn9University of Newcastle, Newcastle upon Tyne, UK.
Gabriela Möslein10University Witten-Herdecke, Wuppertal, Germany.
Inge Bernstein11Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, Denmark.
Kirsi Pylvänäinen12Central Finland Central Hospital, Education and Research, Jyväskylä, Finland.
Laura Renkonen-Sinisalo2Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Helsinki, Finland.
Anna Lepistö2Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Helsinki, Finland.
Annika Lindblom14Karolinska Institutet, Stockholm, Sweden.
John-Paul Plazzer5The Royal Melbourne Hospital, Melbourne, Australia.
Douglas Tjandra6University of Melbourne, Melbourne, Australia.
Huw Thomas15St Mark's Hospital, Department of Surgery and Cancer, Imperial College London, London, UK.
Kate Green7University of Manchester & Manchester University Hospitals Foundation Trust, Manchester, UK.
Fiona Lalloo7University of Manchester & Manchester University Hospitals Foundation Trust, Manchester, UK.
Emma J Crosbie16University of Manchester and St Mary's Hospital, Manchester, UK.
James Hill7University of Manchester & Manchester University Hospitals Foundation Trust, Manchester, UK.
Gabriel Capella17Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, Barcelona, Spain.
Marta Pineda17Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, Barcelona, Spain.
Matilde Navarro17Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, Barcelona, Spain.
Joan Brunet Vidal17Hereditary Cancer Program, Catalan Institute of Oncology, Insititut d'Investigació Biomèdica de Bellvitge (IDIBELL), ONCOBELL Program, L'Hospitalet de Llobregat, Barcelona, Spain.
Karina Rønlund19Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark.
Randi Thyregaard Nielsen20Department of Surgery, Regional Hospital West Jutland, Egtved, Denmark.
Mette Yilmaz21Department of Oncology, Aalborg University Hospital, Aalborg, Denmark.
Louise Laurberg Elvang22Department of Pathology, Herlev Gentofte University Hospital, Herlev, Denmark.
Lior Katz23High Risk and GI Cancer prevention Clinic, Gatro-Oncology Unit, The Department of Gastroenterology, Sheba Medical Center, Ramat Gan, Israel.
Maartje Nielsen24Leids Universitair Medisch Centrum, Leiden, Netherlands.
Sanne W Ten Broeke24Leids Universitair Medisch Centrum, Leiden, Netherlands.
Sigve Nakken1Department of Tumor Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway.
Eivind Hovig1Department of Tumor Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway.
Lone Sunde26Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark.
Matthias Kloor27Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Magnus V Knebel Doeberitz27Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Aysel Ahadova27Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
Noralane Lindor29Department of Health Sciences Research, Mayo Clinic, Scottsdale, AZ USA.
Verena Steinke-Lange30Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.
Elke Holinski-Feder30Medizinische Klinik und Poliklinik IV, Campus Innenstadt, Klinikum der Universität München, Munich, Germany.
Jukka-Pekka Mecklin32Department of Surgery, Central Finland Central Hospital, Jyväskylä, Finland.
Pål Møller1Department of Tumor Biology, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway.

Funding

Department of Health NIHR-CS-012-009Medical Research Council G0100496
6 · The paper itself

Abstract

backgroundWe previously reported that in pathogenic mismatch repair (

methodsThe Prospective Lynch Syndrome Database (PLSD) that records outcomes of surveillance was examined to determine survival after colon cancer in relation to the time since previous colonoscopy and pathological stage. Only

resultsNinety-nine

conclusionsIn

Indexed as

Cancer stageColon cancerColonoscopyLynch syndromeSurveillanceSurvival

Identifiers

PMID31636762
PMCPMC6792227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.