Evidence map›Paper›PMID 31636695›Full record

ArticleChinese medicine2019

Dynamic observation and analysis of metabolic response to moxibustion stimulation on ethanol-induced gastric mucosal lesions (GML) rats.

Yuan Zhang, Miao-Sen Huang, Cai-Chun Liu, Lin-Yu Lian, Jia-Cheng Shen, Qi-da He, Ying-Jie Wang, Long-Bin Zhang, Mi Liu, Zong-Bao Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chinese medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yuan Zhang1Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102 China.
Miao-Sen Huang *1Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102 China.
Cai-Chun Liu1Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102 China.
Lin-Yu Lian1Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102 China.
Jia-Cheng Shen1Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102 China.
Qi-da He1Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102 China.
Ying-Jie Wang1Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102 China.
Long-Bin Zhang1Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102 China.
Mi Liu2College of Acupuncture and Moxibustion, Hunan University of Traditional Chinese Medicine, Changsha, 410208 China.
Zong-Bao Yang1Cancer Research Center, School of Medicine, Xiamen University, Xiamen, 361102 China.
Xiamen University · CNHunan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric mucosal lesion (GML) is the initiating pathological process in many refractory gastric diseases. And moxibustion is an increasingly popular alternative therapy that prevents and treats diseases. However, there are few published reports about developing pathology of GML and therapeutic mechanism of moxibustion treatment on GML. In this study, we investigated pathology of GML and therapeutic mechanism of moxibustion treatment on GML.

methodsThe male Sprague-Dawley (SD) rats were induced by intragastric administration of 75% ethanol after fasting for 24 h and treated by moxibustion at Zusanli (ST36) and Liangmen (ST21) for 1 day, 4 days or 7 days. Then we applied

resultsMoxibustion intervention showed a beneficial effect on GML by modulating comprehensive metabolic alterations caused by GML, including energy metabolism, membrane metabolism, cellular active and neurotransmitters function.

conclusionsMoxibustion can effectively treat gastric mucosal damage and effectively regulate the concentration of some related differential metabolites to maintain the stability of the metabolic pathway.

Indexed as

1H NMRDynamic analysisGastric mucosal lesionMetabolomicsMoxibustion

Identifiers

PMID31636695
PMCPMC6794790
OpenAlexW2981025773

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.