Evidence map›Paper›PMID 31636627›Full record

ArticleFrontiers in immunology2019

Vitamin D Receptor Gene Polymorphisms Are Associated With Leprosy in Southern Brazil.

Afonso Carrasco Pepineli, Hugo Vicentin Alves, Bruna Tiaki Tiyo, Luciana Conci Macedo, Lorena Visentainer, Quirino Alves de Lima Neto, Joana Maira Valentini Zacarias, Ana Maria Sell, Jeane Eliete Laguila Visentainer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Vitamin D Receptor rs7975232 (Journal of clinical medicine · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Journal of personalized medicine · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Afonso Carrasco PepineliLaboratory of Immunogenetics, Department of Basic Health Sciences, Maringá State University (UEM), Maringá, Brazil.
Hugo Vicentin AlvesLaboratory of Immunogenetics, Department of Basic Health Sciences, Maringá State University (UEM), Maringá, Brazil.
Bruna Tiaki TiyoLaboratory of Immunogenetics, Department of Basic Health Sciences, Maringá State University (UEM), Maringá, Brazil.
Luciana Conci MacedoLaboratory of Immunogenetics, Department of Basic Health Sciences, Maringá State University (UEM), Maringá, Brazil.
Lorena VisentainerDepartment of Medicine, Faculty of Medical Sciences, Campinas State University (UNICAMP), São Paulo, Brazil.
Quirino Alves de Lima NetoLaboratory of Immunogenetics, Department of Basic Health Sciences, Maringá State University (UEM), Maringá, Brazil.
Joana Maira Valentini ZacariasLaboratory of Immunogenetics, Department of Basic Health Sciences, Maringá State University (UEM), Maringá, Brazil.
Ana Maria SellLaboratory of Immunogenetics, Department of Basic Health Sciences, Maringá State University (UEM), Maringá, Brazil.
Jeane Eliete Laguila VisentainerLaboratory of Immunogenetics, Department of Basic Health Sciences, Maringá State University (UEM), Maringá, Brazil.
Universidade Estadual de Maringá · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D, together with its nuclear receptor (VDR), plays an important role in modulating the immune response, decreasing the inflammatory process. Some polymorphisms of the

Indexed as

Polymorphism, Single NucleotideAdolescentAdultAgedAged, 80 and overBrazilCase-Control StudiesChildFemaleGene FrequencyGenetic Predisposition to DiseaseHaplotypesHumansLeprosyMaleMiddle AgedReceptors, CalcitriolVDR protein, humanbiological markerscase-control studiesgene frequenciesgenetic polymorphismmultibacillarypaucibacillary

Identifiers

PMID31636627
PMCPMC6787522
OpenAlexW2971058344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.