ArticleFrontiers in neuroscience2019
Differential Influence of Acupuncture Somatosensory and Cognitive/Affective Components on Functional Brain Connectivity and Pain Reduction During Low Back Pain State.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
What it found
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Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Functional brain alterations associated with acupuncture for chronic pain: a scoping review of fMRI studies.Frontiers in neuroscience · 2026Pooled it
- Neuroimaging evidence for central mechanisms of acupuncture in non-specific low back pain: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Acupuncture for the Management of Low Back Pain.Current pain and headache reports · 2021Pooled it
- Neuroimaging Studies of Acupuncture on Low Back Pain: A Systematic Review.Frontiers in neuroscience · 2021Pooled it
- A meta-analysis of neuroimaging evidence for acupuncture-mediated modulation of altered central pain processing in patients with chronic pain.Frontiers in neurologyPooled it
- A true response of the brain network during electroacupuncture stimulation at scalp acupoints: An fMRI with simultaneous EAS study.Brain and behavior · 2023Trial
- Modulation of Brain Activity in Patients with Acute Non-Specific Low Back Pain by Wentong Guan Therapy: A Functional Near-Infrared Spectroscopy Study.Journal of pain research · 2026Article
- Decoding the mechanisms of acupuncture by neuroimaging: an integrated review from networks to molecules.Frontiers in human neuroscience · 2026Review
- Beyond Needling: Integrating a Bayesian Brain Model into Acupuncture Treatment.Brain sciences · 2025Review
- Research status and trends of functional magnetic resonance imaging technology in the field of acupuncture: a bibliometric analysis over the past two decades.Frontiers in neuroscience · 2025Review
- Cognitive and affective interaction with somatosensory afference in acupuncture-a specific brain response to compound stimulus.Frontiers in human neuroscience · 2023Article
- Acupuncture mechanism studies employing task-based fMRI: a scoping review protocol.Systematic reviews · 2022Article
- The role of visual expectations in acupuncture analgesia: A quantitative electroencephalography study.Molecular pain · 2022Article
- The altered intrinsic functional connectivity after acupuncture at shenmen (HT7) in acute sleep deprivation.Frontiers in neurology · 2022Article
- Brain Mechanism of Acupuncture Treatment of Chronic Pain: An Individual-Level Positron Emission Tomography Study.Frontiers in neurology · 2022Article
- Early Fractional Amplitude of Low Frequency Fluctuation Can Predict the Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Migraine Without Aura.Frontiers in molecular neuroscience · 2022Article
- Cognitive components of acupuncture treatment.Integrative medicine research · 2021Article
- 3D magnetic resonance spectroscopic imaging reveals links between brain metabolites and multidimensional pain features in fibromyalgia.European journal of pain (London, England) · 2021Article
- Imagined and Actual Acupuncture Effects on Chronic Low Back Pain: A Preliminary Study.Neural plasticity · 2020Article
- Resting-State Functional Connectivity Patterns Predict Acupuncture Treatment Response in Primary Dysmenorrhea.Frontiers in neuroscience · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The underlying mechanism of pain reduction by acupuncture is still unclear, because acupuncture treatment involves multidimensional factors. In this study, we investigated the differential influence of acupuncture components on brain functional connectivity and on pain reduction. We used a specific form of sham acupuncture (phantom acupuncture; PHNT), which only has a needling-credibility (a belief that they were treated with real acupuncture needles), while real acupuncture (REAL) has a somatosensory needling stimulation, as well as a needling-credibility. Forty-three patients with low back pain were randomized into the REAL group (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.