Evidence map›Paper›PMID 31636380›Full record

ArticleMolecular psychiatry2020

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Joshua C Bis, Xueqiu Jian, Brian W Kunkle, Yuning Chen, Kara L Hamilton-Nelson, William S Bush, William J Salerno, Daniel Lancour, Yiyi Ma, Alan E Renton and 91 more

Abstract readPublished Erratum
In one paragraph

Article in Molecular psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

101 authors.

Joshua C Bis *Department of Medicine (General Internal Medicine), University of Washington, Seattle, WA, USA.
Xueqiu Jian *Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
Brian W Kunkle *John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL, USA.
Yuning Chen *Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7358-7055
Kara L Hamilton-NelsonJohn P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL, USA.
William S BushCase Western Reserve University, Cleveland Heights, OH, USA.
William J SalernoHuman Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Daniel LancourDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7266-1022
Yiyi MaDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.
Alan E RentonDepartment of Neuroscience and Ronald M Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-6702-8268
Edoardo MarcoraDepartment of Neuroscience and Ronald M Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
John J FarrellDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.
Yi ZhaoUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Liming QuUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Shahzad AhmadErasmus University Medical Center, Rotterdam, Netherlands.
Najaf AminInserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
Philippe AmouyelInserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.ORCID http://orcid.org/0000-0001-9088-234X
Gary W BeechamJohn P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL, USA.
Jennifer E BelowDepartment of Medical Genetics, Vanderbilt University Medical Center, Nashville, TN, USA.
Dominique CampionDepartment of Genetics and CNR-MAJ, Normandie Université, UNIROUEN, Inserm U1245 and Rouen University Hospital, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
Laura CantwellUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Camille CharbonnierDepartment of Genetics and CNR-MAJ, Normandie Université, UNIROUEN, Inserm U1245 and Rouen University Hospital, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
Jaeyoon ChungDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6431-9454
Paul K CraneDepartment of Medicine (General Internal Medicine), University of Washington, Seattle, WA, USA.
Carlos CruchagaDepartment of Psychiatry, Washington University, St. Louis, MO, USA.
L Adrienne CupplesDepartments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Jean-François DartiguesUniversity of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, F-33000, Bordeaux, France.
Stéphanie DebetteUniversity of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, F-33000, Bordeaux, France.
Jean-François DeleuzeCentre National de Recherche en Génomique Humaine, Institut François Jacob, Direction de le Recherche Fondamentale, CEA, Evry, France.
Lucinda FultonMcDonnell Genome Institute, Washington University, St. Louis, MO, USA.
Stacey B GabrielBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Emmanuelle GeninInserm UMR-1078, CHRU Brest, Université Brest, Brest, France.
Richard A GibbsHuman Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Alison GoateDepartment of Neuroscience and Ronald M Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-0576-2472
Benjamin Grenier-BoleyInserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
Namrata GuptaBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Jonathan L HainesCase Western Reserve University, Cleveland Heights, OH, USA.
Aki S HavulinnaInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Seppo HelisalmiInstitute of Clinical Medicine - Neurology and Department of Neurology, University of Eastern Finland, Kuopio, Finland.
Mikko HiltunenInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Daniel P HowriganProgram in Medical and Population Genetics and Genetic Analysis Platform, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
M Arfan IkramErasmus University Medical Center, Rotterdam, Netherlands.ORCID http://orcid.org/0000-0003-0372-8585
Jaakko KaprioInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0002-3716-2455
Jan KonradDepartment of Psychiatry, Washington University, St. Louis, MO, USA.
Amanda KuzmaUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Eric S LanderBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Mark LathropMcGill University and Génome Québec Innovation Centre, Montréal, Canada.
Terho LehtimäkiDepartment of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Honghuang LinDepartment of Medicine (Computational Biomedicine), Boston University School of Medicine, Boston, MA, USA.ORCID http://orcid.org/0000-0003-3043-3942
Kari MattilaDepartment of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Richard MayeuxColumbia University, New York, NY, USA.
Donna M MuznyHuman Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Waleed NasserHuman Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Benjamin NealeProgram in Medical and Population Genetics and Genetic Analysis Platform, Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-1513-6077
Kwangsik NhoIndiana University School of Medicine, Indianapolis, IN, USA.
Gaël NicolasDepartment of Genetics and CNR-MAJ, Normandie Université, UNIROUEN, Inserm U1245 and Rouen University Hospital, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.ORCID http://orcid.org/0000-0001-9391-7800
Devanshi PatelDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.
Margaret A Pericak-VanceJohn P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL, USA.
Markus PerolaInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Bruce M PsatyDepartment of Medicine (General Internal Medicine), University of Washington, Seattle, WA, USA.
Olivier QuenezDepartment of Genetics and CNR-MAJ, Normandie Université, UNIROUEN, Inserm U1245 and Rouen University Hospital, F 76000, Normandy Centre for Genomic and Personalized Medicine, Rouen, France.
Farid RajabliJohn P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL, USA.
Richard RedonInserm, CNRS, Univ. Nantes, CHU Nantes, l'institut du thorax, Nantes, France.
Christiane ReitzColumbia University, New York, NY, USA.
Anne M RemesInstitute of Clinical Medicine - Neurology and Department of Neurology, University of Eastern Finland, Kuopio, Finland.
Veikko SalomaaNational Institute for Health and Welfare, Helsinki, Finland.
Chloe SarnowskiDepartments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Helena SchmidtDepartment of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, Austria.
Michael SchmidtJohn P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL, USA.
Reinhold SchmidtDepartment of Neurology, Clinical Division of Neurogeriatrics, Medical University of Graz, Graz, Austria.
Hilkka SoininenInstitute of Clinical Medicine - Neurology and Department of Neurology, University of Eastern Finland, Kuopio, Finland.
Timothy A ThorntonDepartment of Statistics, University of Washington, Seattle, WA, USA.
Giuseppe TostoColumbia University, New York, NY, USA.
Christophe TzourioUniversity of Bordeaux, Inserm, Bordeaux Population Health Research Center, team VINTAGE, UMR 1219, F-33000, Bordeaux, France.
Sven J van der LeeErasmus University Medical Center, Rotterdam, Netherlands.ORCID http://orcid.org/0000-0003-1606-8643
Cornelia M van DuijnErasmus University Medical Center, Rotterdam, Netherlands.
Otto ValladaresUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Badri VardarajanColumbia University, New York, NY, USA.
Li-San WangUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Weixin WangUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Ellen WijsmanDepartment of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA.
Richard K WilsonMcDonnell Genome Institute, Washington University, St. Louis, MO, USA.
Daniela WittenDepartment of Statistics, University of Washington, Seattle, WA, USA.
Kim C WorleyHuman Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Xiaoling ZhangDepartments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Alzheimer’s Disease Sequencing Project
Celine BellenguezInserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.ORCID http://orcid.org/0000-0002-1240-7874
Jean-Charles LambertInserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.ORCID http://orcid.org/0000-0003-0829-7817
Mitja I KurkiInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Aarno PalotieInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Mark DalyBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-0949-8752
Eric BoerwinkleHuman Genome Sequencing Center and Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Kathryn L LunettaDepartments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.ORCID http://orcid.org/0000-0002-9268-810X
Anita L DestefanoDepartments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Josée DupuisDepartments of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Eden R MartinJohn P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, FL, USA.
Gerard D SchellenbergUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Sudha SeshadriNational Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA.
Adam C Naj *University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-9621-2942
Myriam Fornage *Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.
Lindsay A Farrer *Departments of Biostatistics, Boston University School of Public Health, Boston, MA, USA. farrer@bu.Edu.

Funding

THERAPEUTIC EFFECTS OF INTRA-NASAL INSULIN DETEMIRP50AG005136 · NIA · UNIVERSITY OF WASHINGTON · PI GRABOWSKI, THOMAS J. · 1985 to 2019
$57.2M
Research Education CoreP30AG066462 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Miguel Arce · 2020 to 2026
$30.1M
University of Washington Alzheimer's Disease Research CenterP30AG066509 · NIA · UNIVERSITY OF WASHINGTON · PI Thomas J. Grabowski · 2020 to 2026
$29.0M
NIA NIH HHS P30 AG066462NIA NIH HHS P30 AG066509NIA NIH HHS P50 AG005136
6 · The paper itself

Abstract

A correction to this paper has been published and can be accessed via a link at the top of the paper.

Identifiers

PMID31636380
PMCPMC7387240

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.