Evidence map›Paper›PMID 31636119›Full record

ArticleThe Journal of cell biology2019

Nucleoplasmin is a limiting component in the scaling of nuclear size with cytoplasmic volume.

Pan Chen, Miroslav Tomschik, Katherine M Nelson, John Oakey, Jesse C Gatlin, Daniel L Levy

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Reconstitution of genome remodeling usingFrontiers in cell and developmental biology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. How the chromatin landscape influences nuclear morphology.Frontiers in cell and developmental biology · 2025
    Review
  10. Article
  11. Review
  12. Manipulation of Embryonic Cleavage Geometry Using Magnetic Tweezers.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  13. Nuclear growth and import can be uncoupled.Molecular biology of the cell · 2024
    Article
  14. Article
  15. Article
  16. Regulation of organelle size and organization during development.Seminars in cell & developmental biology · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pan ChenDepartment of Molecular Biology, University of Wyoming, Laramie, WY.ORCID 0000-0001-6821-3510
Miroslav TomschikDepartment of Molecular Biology, University of Wyoming, Laramie, WY.
Katherine M NelsonDepartment of Molecular Biology, University of Wyoming, Laramie, WY.
John OakeyDepartment of Chemical Engineering, University of Wyoming, Laramie, WY.
Jesse C GatlinDepartment of Molecular Biology, University of Wyoming, Laramie, WY.
Daniel L LevyDepartment of Molecular Biology, University of Wyoming, Laramie, WY dlevy1@uwyo.edu.ORCID 0000-0002-7853-3275
University of Wyoming · US

Funding

Wyoming INBRE Phase 4- Equipment Supplement for x-ray diffractometer for Center for Advanced Scientific InstrumentationP20GM103432 · NIGMS · UNIVERSITY OF WYOMING · PI Robert Scott Seville · 2012 to 2026
$56.8M
Mechanisms of nuclear size regulationR35GM134885 · NIGMS · UNIVERSITY OF WYOMING · PI Daniel Leon Levy · 2020 to 2026
$2.5M
Integration of Xenopus extract and microfluidics to study organelle size scalingR01GM113028 · NIGMS · UNIVERSITY OF WYOMING · PI LEVY, DANIEL LEON · 2015 to 2019
$1.3M
NIGMS NIH HHS P20 GM103432NIGMS NIH HHS R01 GM113028NIGMS NIH HHS R35 GM134885
6 · The paper itself

Abstract

How nuclear size is regulated relative to cell size is a fundamental cell biological question. Reductions in both cell and nuclear sizes during

Indexed as

AnimalsCell NucleusCell SizeChromatinCytoplasmCytosolEmbryonic DevelopmentHistonesMicrofluidicsNeoplasmsNucleoplasminsOocytesXenopus laevisXenopus ProteinsChromatinHistonesnpm2 protein, XenopusNucleoplasminsXenopus Proteins

Identifiers

PMID31636119
PMCPMC6891103
OpenAlexW2981387611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.