Evidence map›Paper›PMID 31636071›Full record

SynthesisAntimicrobial agents and chemotherapy2019

A Systematic Review and Meta-analysis of the Prevalence of Community-Onset Bloodstream Infections among Hospitalized Patients in Africa and Asia.

Christian S Marchello, Ariella P Dale, Sruti Pisharody, Matthew P Rubach, John A Crump

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 7 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 7 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. A Systematic Review on Antimicrobial Resistance amongThe American journal of tropical medicine and hygiene · 2020
    Pooled it
  7. Pooled it
  8. Trial
  9. Article
  10. Article
  11. Microbial genomics · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Epidemiology of NontyphoidalAnnals of laboratory medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Christian S MarchelloCentre for International Health, University of Otago, Dunedin, New Zealand.ORCID 0000-0001-6952-9840
Ariella P DaleColorado Department of Public Health and Environment, Denver, Colorado, USA.
Sruti PisharodyDuke University School of Medicine, Durham, North Carolina, USA.
Matthew P RubachDivision of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
John A CrumpCentre for International Health, University of Otago, Dunedin, New Zealand john.crump@otago.ac.nz.
University of Otago · NZColorado Department of Public Health and Environment · USDuke Medical Center · USDuke University · US

Funding

Investigating Febrile Deaths in Tanzania (INDITe)R01AI121378 · NIAID · DUKE UNIVERSITY · PI RUBACH, MATTHEW P · 2016 to 2020
$2.7M
Viral Zoonoses and Severe Febrile Illness in Northern TanzaniaK23AI116869 · NIAID · DUKE UNIVERSITY · PI RUBACH, MATTHEW P · 2016 to 2020
$896k
NIAID NIH HHS K23 AI116869NIAID NIH HHS R01 AI121378
6 · The paper itself

Abstract

Community-onset bloodstream infections (CO-BSI) are major causes of severe febrile illness and death worldwide. In light of new data and the growing problem of antimicrobial resistance (AMR) among pathogens causing BSI, we undertook a systematic review of hospital-based studies of CO-BSI among patients hospitalized with fever. Without restriction to language or country, we searched PubMed, Web of Science, and Scopus for prospective hospital-based studies of culture-confirmed CO-BSI among febrile inpatients. We determined by study the prevalence of BSI among participants, the pathogens responsible for BSI, and the antimicrobial susceptibility patterns of pathogens causing BSI, according to place and time. Thirty-four (77.3%) of 44 eligible studies recruited 29,022 participants in Africa and Asia combined. Among participants in these two regions, the median prevalence of BSI was 12.5% (range, 2.0 to 48.4%); of 3,220 pathogens isolated, 1,119 (34.8%) were

Indexed as

AfricaAnti-Bacterial AgentsAsiaBacteremiaFemaleHumansMalePrevalenceSalmonella entericaStreptococcus pneumoniaeAnti-Bacterial Agentsantimicrobial resistancebacteremiabloodstream infectionscommunity-onset infections

Identifiers

PMID31636071
PMCPMC7187598
OpenAlexW2981493488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.