Evidence map›Paper›PMID 31636011›Full record

ReviewEBioMedicine2019

Systems biology perspective for studying the gut microbiota in human physiology and liver diseases.

Ozlem Altay, Jens Nielsen, Mathias Uhlen, Jan Boren, Adil Mardinoglu

Abstract readReview
In one paragraph

Review in EBioMedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
  6. Food science & nutrition · 2024
    Article
  7. Article
  8. Multiomics Analysis Reveals the Impact of Microbiota on Host Metabolism in Hepatic Steatosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. [Analysis of intestinal flora in patients with chronic rhinosinusitis based on highthroughput sequencing].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
    Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ozlem AltayScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.
Jens NielsenDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden. Electronic address: nielsenj@chalmers.se.
Mathias UhlenScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden. Electronic address: mathias.uhlen@scilifelab.se.
Jan BorenDepartment of Molecular and Clinical Medicine, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address: Jan.Boren@wlab.gu.se.
Adil MardinogluScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, SE1 9RT, United Kingdom. Electronic address: adilm@scilifelab.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advancement in high-throughput sequencing technologies and systems biology approaches have revolutionized our understanding of biological systems and opened a new path to investigate unacknowledged biological phenomena. In parallel, the field of human microbiome research has greatly evolved and the relative contribution of the gut microbiome to health and disease have been systematically explored. This review provides an overview of the network-based and translational systems biology-based studies focusing on the function and composition of gut microbiota. We also discussed the association between the gut microbiome and the overall human physiology, as well as hepatic diseases and other metabolic disorders.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaSystems BiologyHumansLiver DiseasesMetabolismPharmaceutical PreparationsPharmaceutical PreparationsBiomarkerGut microbiomeHost-microbiome interactionsLiver diseasesMetabolic modelsMeta-omicsPersonalized medicineSystems biology

Identifiers

PMID31636011
PMCPMC6945237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.