Evidence map›Paper›PMID 31635694›Full record

ArticleeLife2019

Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment.

Kate A Rawlinson, Francois Lapraz, Edward R Ballister, Mark Terasaki, Jessica Rodgers, Richard J McDowell, Johannes Girstmair, Katharine E Criswell, Miklos Boldogkoi, Fraser Simpson and 5 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 67 citations in OpenAlex.

  1. An Ocean of Opsins.Genome biology and evolution · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 5 countries.

Kate A RawlinsonWellcome Sanger Institute, Hinxton, United Kingdom.ORCID 0000-0001-8297-8405
Francois LaprazUniversité Côte D'Azur, CNRS, Institut de Biologie Valrose, Nice, France.ORCID 0000-0001-9209-2018
Edward R BallisterNew York University School of Medicine, New York, United States.ORCID 0000-0002-4478-2513
Mark TerasakiMarine Biological Laboratory, Woods Hole, United States.ORCID 0000-0003-4964-9401
Jessica RodgersDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Richard J McDowellDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID 0000-0002-6051-106X
Johannes GirstmairCentre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom.ORCID 0000-0001-9029-3625
Katharine E CriswellDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-4004-0192
Miklos BoldogkoiDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Fraser SimpsonCentre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom.
David GouldingWellcome Sanger Institute, Hinxton, United Kingdom.
Claire CormieWellcome Sanger Institute, Hinxton, United Kingdom.
Brian HallDepartment of Biology, Dalhousie University, Halifax, Canada.
Robert J LucasDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID 0000-0002-1088-8029
Maximilian J TelfordCentre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom.ORCID 0000-0002-3749-5620
University of Manchester · GBCentre for Life · GBMarine Biological Laboratory · USWellcome Sanger Institute · GBCentre National de la Recherche Scientifique · FRDalhousie University · CA

Funding

Biotechnology and Biological Sciences Research Council BB/H006966/1
6 · The paper itself

Abstract

Animals detect light using opsin photopigments. Xenopsin, a recently classified subtype of opsin, challenges our views on opsin and photoreceptor evolution. Originally thought to belong to the Gαi-coupled ciliary opsins, xenopsins are now understood to have diverged from ciliary opsins in pre-bilaterian times, but little is known about the cells that deploy these proteins, or if they form a photopigment and drive phototransduction. We characterized xenopsin in a flatworm,

Indexed as

AnimalsBrainCell MembraneEvolution, MolecularEyeGTP-Binding Protein alpha SubunitsHumansLarvaLight Signal TransductionOpsinsPeptidesPhotoreceptor CellsPhotoreceptor Cells, InvertebratePhotoreceptor Cells, VertebratePhylogenyPlatyhelminthsGTP-Binding Protein alpha SubunitsOpsinsPeptidesxenopsinXenopus Proteinsciliary photoreceptordevelopmental biologyevolutionary biologyflatwormMaritigrella crozieriphaosomephotopigmentxenopsin

Identifiers

PMID31635694
PMCPMC6805122
OpenAlexW2981507962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.