Evidence map›Paper›PMID 31635368›Full record

ArticleNutrients2019

Similarities in Metabolic Flexibility and Hunger Hormone Ghrelin Exist between FTO Gene Variants in Response to an Acute Dietary Challenge.

Jessica Danaher, Christos G Stathis, Matthew B Cooke

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Tackling Atherosclerosis via Selected Nutrition.International journal of molecular sciences · 2022
    Review
  3. Review
  4. Article
  5. Nutrients · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Jessica DanaherSchool of Science, College of Science, Engineering and Health, Royal Melbourne Institute of Technology (RMIT) University, Melbourne VIC 3083, Australia. jessica.danaher@rmit.edu.au.ORCID 0000-0002-0201-003X
Christos G StathisInstitute for Health and Sport, Victoria University, Melbourne VIC 3011, Australia. christos.stathis@vu.edu.au.
Matthew B CookeDepartment of Health and Medical Sciences, Faculty of Health, Arts and Design, Swinburne University of Technology, Melbourne VIC 3122, Australia. mbcooke@swin.edu.au.ORCID 0000-0002-4978-4294
RMIT University · AUVictoria University · AUWestern Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rs9939609 polymorphism of the fat mass and obesity-associated (FTO) gene has been associated with obesity, and studies have also shown that environmental/lifestyle interaction such as dietary intake might mediate this effect. The current study investigates the postprandial hormonal regulators of hunger and indirect markers of substrate utilisation and metabolic flexibility following a dietary challenge to determine if suppression of circulating ghrelin levels and/or reduced metabolic flexibility exist between FTO genotypes. One hundred and forty seven healthy, sedentary males and females (29.0 ± 0.7 yrs; 70.2 ± 1.1 kg; 169.1 ± 0.8 cm; 24.5 ± 0.3 kg/m

Indexed as

Energy IntakeGenotypeAdultAllelesAlpha-Ketoglutarate-Dependent Dioxygenase FTOBlood GlucoseDietEnergy MetabolismFemaleGene Expression RegulationGhrelinGlucoseHumansInsulinMaleMiddle AgedAlpha-Ketoglutarate-Dependent Dioxygenase FTOBlood GlucoseFTO protein, humanGhrelinGlucoseInsulinFTOmetabolic flexibilityoral glucose load

Identifiers

PMID31635368
PMCPMC6835809
OpenAlexW2980704542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.