Evidence map›Paper›PMID 31635323›Full record

ArticleCancers2019

EP4 and Class III β-Tubulin Expression in Uterine Smooth Muscle Tumors: Implications for Prognosis and Treatment.

Jocelyn Reader, Amy K Harper, Teklu Legesse, Paul N Staats, Olga Goloubeva, Gautam G Rao, Amy Fulton, Dana M Roque

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Immune Tumor Microenvironment in Ovarian Cancer Ascites.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Eicosanoids in Cancer: Prostaglandin EFrontiers in pharmacology · 2020
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jocelyn ReaderDivision of Gynecologic Oncology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. jreader@som.umaryland.edu.ORCID 0000-0002-9971-9087
Amy K HarperDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA. aharper4@med.wayne.edu.
Teklu LegesseDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Teklu.Legesse@som.umaryland.edu.
Paul N StaatsDepartment of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. pstaats@umm.edu.ORCID 0000-0002-6526-5750
Olga GoloubevaDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA. OGoloubeva@som.umaryland.edu.
Gautam G RaoUniversity of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA. grao@som.umaryland.edu.
Amy FultonUniversity of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA. afulton@som.umaryland.edu.
Dana M RoqueUniversity of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD 21201, USA. droque@som.umaryland.edu.ORCID 0000-0002-7098-6376
University of Maryland, Baltimore · US

Funding

Baltimore Veterans Affairs Merit ReviewBLRD VA I01 BX000169
6 · The paper itself

Abstract

The microtubule-stabilizing agent docetaxel in combination with gemcitabine represents one of the most effective regimens against the aggressive gynecologic tumor leiomyosarcoma (LMS). Upregulation of class III β-tubulin has previously been shown to confer taxane resistance in a variety of human cancers. Prostaglandin E

Indexed as

class III β tubulinEP4leiomyosarcomaPGE2tumorsuterine

Identifiers

PMID31635323
PMCPMC6826612
OpenAlexW2981054004

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.