Evidence map›Paper›PMID 31635304›Full record

ArticleBiomolecules2019

Interaction of a Polyarginine Peptide with Membranes of Different Mechanical Properties.

Matías A Crosio, Matías A Via, Candelaria I Cámara, Agustin Mangiarotti, Mario G Del Pópolo, Natalia Wilke

Abstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Antifungal Peptides SmAPAntibiotics (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. Susceptibility ofMolecules (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Internalization mechanisms of cell-penetrating peptides.Beilstein journal of nanotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matías A CrosioFacultad de Ciencias Químicas, Departamento de Química Biológica Ranwel Caputto, Universidad Nacional de Córdoba, X5000HUA Córdoba, Argentina. matias.crosio@gmail.com.
Matías A ViaICB-CONICET & Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, M5502JMA Mendoza, Argentina. matysvia@gmail.com.ORCID 0000-0003-0687-7279
Candelaria I CámaraFacultad de Ciencias Químicas, Departamento de Fisicoquímica, Universidad Nacional de Cordoba, X5000HUA Córdoba, Argentina. candecamara@gmail.com.
Agustin MangiarottiFacultad de Ciencias Químicas, Departamento de Química Biológica Ranwel Caputto, Universidad Nacional de Córdoba, X5000HUA Córdoba, Argentina. amangiarotti@unc.edu.ar.ORCID 0000-0003-2694-6200
Mario G Del PópoloICB-CONICET & Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, M5502JMA Mendoza, Argentina. mdelpopolo@fcen.uncu.edu.ar.
Natalia WilkeFacultad de Ciencias Químicas, Departamento de Química Biológica Ranwel Caputto, Universidad Nacional de Córdoba, X5000HUA Córdoba, Argentina. natalia.wilke@unc.edu.ar.

Funding

THE MECHANISM OF PROCESSING OF SV40 EARLY RNAP01CA033620 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI PRIVES, CAROL · 1985 to 1992
–
6 · The paper itself

Abstract

The membrane translocation efficiency of cell penetrating peptides (CPPs) has been largely studied, and poly-arginines have been highlighted as particularly active CPPs, especially upon negatively charged membranes. Here we inquire about the influence of membrane mechanical properties in poly-arginine adsorption, penetration and translocation, as well as the subsequent effect on the host membrane. For this, we selected anionic membranes exhibiting different rigidity and fluidity, and exposed them to the nona-arginine KR

Indexed as

Stress, MechanicalAirHydrodynamicsLipid BilayersParticle SizePeptidesSurface PropertiesUnilamellar LiposomesWaterLipid BilayersPeptidespolyarginineUnilamellar LiposomesWatercell penetration peptidesliquid-ordered phasemembrane heterogeneitiesmembrane rheology

Identifiers

PMID31635304
PMCPMC6843195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.