ArticleMaterials (Basel, Switzerland)2019
Tribomechanical Comparison between PVA Hydrogels Obtained Using Different Processing Conditions and Human Cartilage.
Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
23 citing papers in PubMed.
- Biomimetic pHEMA Hydrogels as an Alternative Cartilage-like Model Material for Biotribological Evaluations.ACS omega · 2025Article
- Annealed Polyvinyl Alcohol Hydrogels for Cartilage Replacement: Effects of Synthesis Parameters on Mechanical Properties.Gels (Basel, Switzerland) · 2025Article
- Influence of Glycerol on the Surface Morphology and Crystallinity of Polyvinyl Alcohol Films.Polymers · 2024Article
- Tribomechanical Properties of PVA/NomexGels (Basel, Switzerland) · 2024Article
- Eco-Friendly Production of Polyvinyl Alcohol/Carboxymethyl Cellulose Wound Healing Dressing Containing Sericin.Gels (Basel, Switzerland) · 2024Article
- Hydrogel-Based Strategies for Intervertebral Disc Regeneration: Advances, Challenges and Clinical Prospects.Gels (Basel, Switzerland) · 2024Review
- Release of natural extracts from PVA and PVA-CMC hydrogel wound dressings: a power law swelling/delivery.Frontiers in bioengineering and biotechnology · 2024Article
- Review
- Effects of Non-Conventional Sterilisation Methods on PBO-Reinforced PVA Hydrogels for Cartilage Replacement.Gels (Basel, Switzerland) · 2022Article
- Hydroxyapatite Reinforced Polyvinyl Alcohol/Polyvinyl Pyrrolidone Based Hydrogel for Cartilage Replacement.Gels (Basel, Switzerland) · 2022Article
- Polymeric Hydrogels for Controlled Drug Delivery to Treat Arthritis.Pharmaceutics · 2022Review
- PVA-Based Hydrogels Loaded with Diclofenac for Cartilage Replacement.Gels (Basel, Switzerland) · 2022Article
- An Artificial PVA-BC Composite That Mimics the Biomechanical Properties and Structure of a Natural Intervertebral Disc.Materials (Basel, Switzerland) · 2022Article
- Hydrogels for Treatment of Different Degrees of Osteoarthritis.Frontiers in bioengineering and biotechnology · 2022Review
- In Vitro Wound Dressing Stack Model as a First Step to Evaluate the Behavior of Dressing Materials in Wound Bed-An Assessment of Mass Transport Phenomena in Hydrogel Wound Dressings.Materials (Basel, Switzerland) · 2021Article
- Combinations of Hydrogels and Mesenchymal Stromal Cells (MSCs) for Cartilage Tissue Engineering-A Review of the Literature.Gels (Basel, Switzerland) · 2021Review
- Fabrication and characterization of microstructure-controllable COL-HA-PVA hydrogels for cartilage repair.Journal of materials science. Materials in medicine · 2021Article
- Polymer-Based Carriers in Dental Local Healing-Review and Future Challenges.Materials (Basel, Switzerland) · 2021Review
- Advanced hydrogels for the repair of cartilage defects and regeneration.Bioactive materials · 2021Review
- Applications of Functionalized Hydrogels in the Regeneration of the Intervertebral Disc.BioMed research international · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Designing materials for cartilage replacement raises several challenges due to the complexity of the natural tissue and its unique tribomechanical properties. Poly(vinyl alcohol) (PVA) hydrogels have been explored for such purpose since they are biocompatible, present high chemical stability, and their properties may be tailored through different strategies. In this work, the influence of preparation conditions of PVA hydrogels on its morphology, water absorption capacity, thermotropic behavior, mechanical properties, and tribological performance was evaluated and compared with those of human cartilage (HC). The hydrogels were obtained by cast-drying (CD) and freeze-thawing (FT), in various conditions. It was found that the method of preparation of the PVA hydrogels critically affects their microstructure and performance. CD gels presented a denser structure, absorbed less water, were stiffer, dissipated less energy, and withstood higher loads than FT gels. Moreover, they led to friction coefficients against stainless steel comparable with those of HC. Overall, CD hydrogels had a closer performance to natural HC, when compared to FT ones.
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Registered trials
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