ArticleMaterials (Basel, Switzerland)2019
Comparison of Bone Regeneration between Porcine-Derived and Bovine-Derived Xenografts in Rat Calvarial Defects: A Non-Inferiority Study.
Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative evaluation of porcine and bovine bone xenografts in bone grafting: a systematic review and meta-analysis.International journal of implant dentistry · 2025Pooled it
- Breaking the immune barrier: construction of cartilaginous organoids using alpha-1,3-galactosyltransferase-deficient pig cartilage-derived particles.Journal of translational medicine · 2026Article
- Human umbilical cord-derived mesenchymal stem cells/Bio-Oss granules composite prevents medication-related osteonecrosis of the jaw in a rat model.Frontiers in bioengineering and biotechnology · 2026Article
- Evaluation of the osteoconductive potential of Croton lechleri sap associated with collagen or wax-based carriers in critical-size bone defects in rat calvaria.Acta cirurgica brasileira · 2026Article
- Optical Coherence Tomography, Stereomicroscopic, and Histological Aspects of Bone Regeneration on Rat Calvaria in the Presence of Bovine Xenograft or Titanium-Reinforced Hydroxyapatite.Journal of functional biomaterials · 2026Article
- Cranial Bone Repair and Regeneration After Trauma: Forensic and Clinical Medico-Legal Consequences.Bioengineering (Basel, Switzerland) · 2025Review
- Bone Regeneration in Defects Created on Rat Calvaria Grafted with Porcine Xenograft and Synthetic Hydroxyapatite Reinforced with Titanium Particles-A Microscopic and Histological Study.Journal of functional biomaterials · 2025Article
- An evaluation of novel AMP2-coated electrospun composite scaffolds for intraoral bone regeneration: a proof-of-conceptFrontiers in bioengineering and biotechnology · 2025Article
- Bovine Mineral Grafting Affects the Hydrophilicity of Dental Implant Surfaces: An In Vitro Study.Materials (Basel, Switzerland) · 2024Article
- Comparing the effects of BoneClinical and experimental dental research · 2024Article
- A Comparative Study of HA/DBM Compounds Derived from Bovine and Porcine for Bone Regeneration.Journal of functional biomaterials · 2023Article
- Effect of Porcine- and Bovine-Derived Xenografts with Hydroxypropyl Methylcellulose for Bone Formation in Rabbit Calvaria Defects.Materials (Basel, Switzerland) · 2023Article
- Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine.Biomaterials research · 2023Review
- Efficiency analysis of commercial polymeric membranes for bone regeneration in rat cranial defects.Acta cirurgica brasileira · 2023Article
- Evaluation of a New Porcine Bone Graft on the Repair of Surgically Created Critical Bone Defects in Rat Calvaria: Histomorphometric and Microtomographic Study.Journal of functional biomaterials · 2022Article
- In Vivo Biocompatibility Investigation of an Injectable Calcium Carbonate (Vaterite) as a Bone Substitute including Compositional Analysis via SEM-EDX Technology.International journal of molecular sciences · 2022Article
- Development and characterization of poultry collagen-based hybrid hydrogels for bone regeneration.Acta cirurgica brasileira · 2022Article
- Augmentation Stability of Guided Bone Regeneration for Peri-Implant Dehiscence Defects with L-shaped Porcine-Derived Block Bone Substitute.Materials (Basel, Switzerland) · 2021Article
- Evaluation of 1-Ethyl-3-(3-Dimethylaminopropyl) Carbodiimide Cross-Linked Collagen Membranes for Guided Bone Regeneration in Beagle Dogs.Materials (Basel, Switzerland) · 2020Article
- Photobiomodulation Therapy Associated with Heterologous Fibrin Biopolymer and Bovine Bone Matrix Helps to Reconstruct Long Bones.Biomolecules · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to compare the bone-regeneration capacity of porcine-derived xenografts to bovine-derived xenografts in the rat calvarial defect model. The observation of surface morphology and in vitro cell studies were conducted prior to the animal study. Defects with a diameter of 8 mm were created in calvaria of 20 rats. The rats were randomly treated with porcine-derived (Bone-XP group) or bovine-derived xenografts (Bio-Oss group) and sacrificed at 4 and 8 weeks after surgery. The new bone regeneration was evaluated by micro-computed tomography (μCT) and histomorphometric analyses. In the cell study, the extracts of Bone-XP and Bio-Oss showed a positive effect on the regulation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) without cytotoxicity. The new bone volume of Bone-XP (17.52 ± 3.78% at 4 weeks and 32.09 ± 3.51% at 8 weeks) was similar to that of Bio-Oss (11.6 ± 3.88% at 4 weeks and 25.89 ± 7.43% at 8 weeks) (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.