Evidence map›Paper›PMID 31635256›Full record

ReviewMicroorganisms2019

Current Status and Potential Applications of Underexplored Prokaryotes.

Kian Mau Goh, Saleha Shahar, Kok-Gan Chan, Chun Shiong Chong, Syazwani Itri Amran, Mohd Helmi Sani, Iffah Izzati Zakaria, Ummirul Mukminin Kahar

Abstract readReview
In one paragraph

Review in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Candidatus List No. 6.International journal of systematic and evolutionary microbiology · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. 'Microbial genomics · 2023
    Article
  8. Article
  9. Genome Analysis ofMicroorganisms · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kian Mau GohFaculty of Science, Universiti Teknologi Malaysia, Skudai 81310, Johor, Malaysia. gohkianmau@utm.my.ORCID 0000-0002-2839-8722
Saleha ShaharFaculty of Science, Universiti Teknologi Malaysia, Skudai 81310, Johor, Malaysia. salehas@utm.my.
Kok-Gan ChanDivision of Genetics and Molecular Biology, Institute of Biological Science, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia. kokgan@um.edu.my.ORCID 0000-0002-1883-1115
Chun Shiong ChongFaculty of Science, Universiti Teknologi Malaysia, Skudai 81310, Johor, Malaysia. cschong@utm.my.
Syazwani Itri AmranFaculty of Science, Universiti Teknologi Malaysia, Skudai 81310, Johor, Malaysia. syazwaniitri@utm.my.
Mohd Helmi SaniFaculty of Science, Universiti Teknologi Malaysia, Skudai 81310, Johor, Malaysia. helmisani@utm.my.
Iffah Izzati ZakariaMalaysia Genome Institute, National Institutes of Biotechnology Malaysia, Jalan Bangi, Kajang 43000, Selangor, Malaysia. iffahizzati@nibm.my.
Ummirul Mukminin KaharMalaysia Genome Institute, National Institutes of Biotechnology Malaysia, Jalan Bangi, Kajang 43000, Selangor, Malaysia. ummirul@nibm.my.ORCID 0000-0003-3041-985X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thousands of prokaryotic genera have been published, but methodological bias in the study of prokaryotes is noted. Prokaryotes that are relatively easy to isolate have been well-studied from multiple aspects. Massive quantities of experimental findings and knowledge generated from the well-known prokaryotic strains are inundating scientific publications. However, researchers may neglect or pay little attention to the uncommon prokaryotes and hard-to-cultivate microorganisms. In this review, we provide a systematic update on the discovery of underexplored culturable and unculturable prokaryotes and discuss the insights accumulated from various research efforts. Examining these neglected prokaryotes may elucidate their novelties and functions and pave the way for their industrial applications. In addition, we hope that this review will prompt the scientific community to reconsider these untapped pragmatic resources.

Indexed as

ex situ diffusion bioreactorichipmetagenome-assembled genomerare microorganismsshotgun metagenome sequencingunculturable bacteria

Identifiers

PMID31635256
PMCPMC6843859

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.