ArticleDiagnostics (Basel, Switzerland)2019
Spontaneous Splenic Rupture as a Rare Initial Presentation in an Acute Lymphoblastic Leukemia Patient.
Article in Diagnostics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 9 citations in OpenAlex.
- Dynamic lineage evolution in hematologic malignancies: a case report of B-ALL Progressing to CMML and AML.Annals of hematology · 2026Article
- Article
- Spontaneous Rupture of the Testicle Secondary to Coughing in a Patient With New-Onset Heart Failure: A Case Report.Cureus · 2025Article
- Unusual symptoms reveal a rare splenic lymphoma: a case report of PS-DLBCL with neck and shoulder pain as the initial presentation.Frontiers in oncology · 2025Article
- Spontaneous splenic rupture: A rare complication of acute myeloid leukemia. Report of a case.Annals of medicine and surgery (2012) · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
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Abstract
A spontaneous rupture of the spleen is a rare but critical diagnosis of an acute abdomen, which may accompany unspecific symptoms mimicking acute pancreatitis, rupture of aortic aneurism, or acute coronary syndrome, delaying diagnosis and treatment. In patients that have experienced a severe spleen rupture, hypovolemic shock may cause catastrophic clinical outcomes. Therefore, early diagnosis is very important in order for physicians to declare the etiology for prevention and timely correction of the shock status. Several causes of spontaneous splenic rupture have been reported, including infection, vasculitis, pancreatitis, or hematological malignancies. Acute lymphoblastic leukemia (ALL) remains a rare but important cause of non-traumatic splenic rupture that physicians are required to assess for. Here, we describe a case presenting an acute abdomen due to spontaneous spleen rupture as the first manifestation. The purpose of this case report was to highlight the importance of considering spontaneous ruptures of the spleen as a rare but critical differential diagnosis of an acute abdomen, especially in patients with acute lymphoblastic leukemia.
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