Evidence map›Paper›PMID 31635168›Full record

ArticleInternational journal of molecular sciences2019

Inhibitory Effects of

Zhihao Chen, Eunjin Cho, Jinkyung Lee, Sunwoo Lee, Tae-Hoon Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  6. Molecules (Basel, Switzerland) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhihao ChenDepartment of Molecular Medicine (BK21plus), Chonnam National University Graduate School, Gwangju 61186, Korea. chinaczhihao@gmail.com.ORCID 0000-0002-8433-5400
Eunjin ChoDepartment of Oral Biochemistry, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea. ag8414@gmail.com.
Jinkyung LeeDepartment of Oral Biochemistry, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea. wlsrud1945@naver.com.ORCID 0000-0003-1613-6490
Sunwoo LeeDepartment of Chemistry, Chonnam National University, Gwangju 61186, Korea. sunwoo@chonnam.ac.kr.
Tae-Hoon LeeDepartment of Molecular Medicine (BK21plus), Chonnam National University Graduate School, Gwangju 61186, Korea. thlee83@jnu.ac.kr.
Chonnam National University · KR

Funding

Ministry of Science, ICT and Future Planning 2017R1A2B2005938
6 · The paper itself

Abstract

Osteoclasts are poly-nuclear cells that resorb mineral components from old or damaged bone tissue. Primary mononuclear cells are activated by receptor activator of nuclear factor kappa-Β ligand (RANKL) and differentiate into large multinucleated cells. Dysregulation of osteoclast differentiation can lead to pathological bone loss and destruction. Many studies have focused on the development of new molecules to regulate RANKL-mediated signaling. In this study,

Indexed as

AcetamidesAnimalsCell DifferentiationCells, CulturedGene Expression RegulationHumansIntracellular Signaling Peptides and ProteinsMacrophagesMiceMice, Inbred C57BLOsteoclastsOsteogenesisRANK LigandAcetamidesIntracellular Signaling Peptides and ProteinsRANK LigandTifab protein, humanTNFSF11 protein, humanbone resorptionosteoclastogenesispiperazineTRAF6

Identifiers

PMID31635168
PMCPMC6829416
OpenAlexW2981234609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.