Evidence map›Paper›PMID 31635130›Full record

ArticleCells2019

Increased Expression of Meteorin-Like Hormone in Type 2 Diabetes and Obesity and Its Association with Irisin.

Irina AlKhairi, Preethi Cherian, Mohamed Abu-Farha, Ashraf Al Madhoun, Rasheeba Nizam, Motasem Melhem, Mohamed Jamal, Suleiman Al-Sabah, Hamad Ali, Jaakko Tuomilehto and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 83 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Irina AlKhairiDepartment of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. irina.alkhairi@dasmaninstitute.org.
Preethi CherianDepartment of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. preethi.cherian@dasmaninstitute.org.
Mohamed Abu-FarhaDepartment of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. mohamed.abufarha@dasmaninstitute.org.
Ashraf Al MadhounDepartment of Genetic and Bioinformatics, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. ashraf.madhoun@dasmaninstitute.org.
Rasheeba NizamDepartment of Genetic and Bioinformatics, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. rasheeba.iqbal@dasmaninstitute.org.
Motasem MelhemDepartment of Genetic and Bioinformatics, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. motasem.melhem@dasmaninstitute.org.
Mohamed JamalDepartment of Surgery, Faculty of Medicine, Health Sciences Centre, Kuwait University, Sulaibekhat 90805, Kuwait. mjamal110@gmail.com.
Suleiman Al-SabahDepartment of Pharmacology & Toxicology, Faculty of Medicine, Health Sciences Centre, Kuwait University, Sulaibekhat 90805, Kuwait. suleiman@HSC.EDU.KW.
Hamad AliDepartment of Genetic and Bioinformatics, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. hamad.ali@HSC.EDU.KW.
Jaakko TuomilehtoResearch division, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. tuomilehto@hotmail.com.
Fahd Al-MullaDepartment of Genetic and Bioinformatics, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. fahd.almulla@dasmaninstitute.org.
Jehad AbubakerDepartment of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Kuwait City 15462, Kuwait. jehad.abubakr@dasmaninstitute.org.
Dasman Diabetes Institute · KWKuwait University · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type 2 diabetes (T2D) is a growing pandemic associated with metabolic dysregulation and chronic inflammation. Meteorin-like hormone (METRNL) is an adipomyokine that is linked to T2D. Our objective was to evaluate the changes in METRNL levels in T2D and obesity and assess the association of METRNL levels with irisin. Overall, 228 Arab individuals were enrolled. Plasma levels of METRNL and irisin were assessed using immunoassay. Plasma levels of METRNL and irisin were significantly higher in T2D patients than in non-diabetic patients (

Indexed as

AdipokinesAdultAnthropometryDiabetes Mellitus, Type 2Edetic AcidEnzyme-Linked Immunosorbent AssayFemaleFibronectinsHumansImmunoassayMaleObesityAdipokinesEdetic AcidFibronectinsFNDC5 protein, humanMetrnl protein, humanadipomyokinesirisinMeteorin-like hormoneMETRNLobesitytype 2 diabetes

Identifiers

PMID31635130
PMCPMC6829873
OpenAlexW2981169505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.